8 documents found, page 1 of 1
Safety of a mRNA COVID-19 Vaccine in Patients with Indolent Systemic Mastocytosis
Gouveia, Joana; Rodrigues, Maria Alexandra; Fernandes, Iolanda; Cabral, Renata; Falcão, HelenaN/a.; N/a.
Quality of life in heterosexual menopausal women: The indirect effect of sexual...
Pereira, M. Graça; Bernardo, Ana Cristina; Fernandes, Iolanda; Almeida, Ana C.Menopause may negatively impact Quality of Life (QoL). Our study used a cross-sectional design and research participants were 99 women in natural menopause. In our study, we analyzed the relationship between age at menopause onset, hormone therapy use, duration of couple relationship, menopause duration, psychological morbidity, marital satisfaction, menopause representations, and QoL following the Wilson and C...
Treatment of Primary Cutaneous Anaplastic Large-Cell Lymphoma with Brentuximab ...
Ferreira, Sandra; Fernandes, Iolanda; Cabral, Renata; Lima, MargaridaBrentuximab vedotin is approved by the Food and Drug Administration (FDA) and by the European Medicines Agency (EMA) for the treatment of adult patients with CD30-positive primary cutaneous T-cell lymphomas, refractory to at least one previous line of therapy. The authors report two clinical cases of primary cutaneous anaplastic large-cell lymphoma treated with brentuximab vedotin, with different clinical respo...
IL-31 and IL-8 in Cutaneous T-Cell Lymphoma: Looking for Their Role in Itch
Abreu, Maria; Miranda, Marta; Castro, M; Fernandes, Iolanda; Cabral, Renata; Santos, Ana Helena; Fonseca, Sonia; Rodrigues, João; Leander, MagdalenaThe itch associated with cutaneous T-cell lymphoma (CTCL), including Mycosis Fungoides (MF) and Sézary syndrome (SS), is often severe and poorly responsive to treatment with antihistamines. Recent studies have highlighted the possible role of interleukins in nonhistaminergic itch. We investigated the role of IL-31 and IL-8 in CTCL, concerning disease severity and associated itch. Serum samples of 27 patients wi...
Manifestações Cutâneas nas Mastocitoses: Atualização
Ferreira, Sandra; Fernandes, Iolanda; Cabral, Renata; Machado, Susana; Lima, Margarida; Selores, ManuelaIntrodução: As mastocitoses caraterizam-se pela expansão clonal de mastócitos, com acumulação de mastócitos morfológica e imunofenotipicamente anormais em diferentes órgãos. A pele é o órgão mais frequentemente envolvido. Virtualmente, todas as crianças e mais de 80% dos adultos com mastocitose apresentam lesões cutâneas. Material e Métodos: O presente artigo descreve os sinais e sintomas associados à mastocito...
Cutaneous Manifestations in Mastocytosis: Update
Ferreira, Sandra; Fernandes, Iolanda; Cabral, Renata; Machado, Susana; Lima, Margarida; Selores, ManuelaIntroduction: Mastocytosis is characterized by the clonal expansion of morphological and immunophenotypically abnormal mast cells in different organs. The skin is the most frequently affected tissue. Virtually all children and more than 80% of adult patients with mastocytosis show cutaneous lesions.Material and Methods: The present article describes the symptoms and signs in cutaneous mastocytosis, based on the...
Phototherapy as a First Line Treatment for Mycosis Fungoides: A 10-year Retrosp...
Azevedo, Alexandra; Fernandes, Iolanda; Cabral, Renata; Lima, Margarida; Amorim, Isabel; Selores, ManuelaIntroduction: Phototherapy, particularly psoralen plus ultraviolet A (PUVA) and narrowband ultraviolet B (nbUVB), is a mainstay in the treatment of Mycosis Fungoides (MF). Methods: We analyzed outcomes of MF patients treated for the first time with either PUVA or nbUVB at the Photodermatology Unit, in the Department of Dermatology of Centro Hospitalar Universitário do Porto, from 2007 to 2017. The primary outco...
The syllable in the relation to writing: branching onsets in the writing of chi...
Pampim, Moisés; Reis, Diana; Mendonça, Cristiana; Fernandes, IolandaThe syllable is a unit of the phonological system of human languages that has been the subject of numerous studies in language and language acquisition. Using longitudinal data from the online corpus EFFE-On, this article focuses on the evaluation of children's written performance with respect to the order of acquisition of the syllable structure, in particular the analysis of branching Onsets (obstruent+liquid...