43 documents found, page 1 of 5

Biofilm matrix regulation by Candida glabrata Zap1 under acidic conditions: tra...

The vaginal acidic environment potentiates the formation of Candida glabrata biofilms, leading to complicated and recurrent infections. Importantly, the production of matrix is known to contribute to the recalcitrant features of Candida biofilms. In this study, we reveal that Zap1 regulates the matrix of C. glabrata acidic biofilms and analyzed the modulation of their transcriptome (by microarrays) and matrix p...

Estrutura, “petrofabric” e paragénese do índice tungsteno-aurífero de Ruivos ...

In Ponte da Barca region, inner-granite, the intersections of multistage shear zones, N0°-7°E / N70°E, are the main focus of hydrothermal Au + As mineralization, especially when a third set of ruptures (~N30°E), reticulates the adjacent volume of massif. The detailed study of the Boivão – Ruivos shear junction showed that the more varied are the strikes and deeps of the ruptures that affect a granite compartmen...

Non-Invasive heart failure telemonitoring: A crossover technological Trial

Modelos de gestão de oferta alimentar em refeitórios escolares do Alto Minho - ...

Promoção da saúde mental às famílias/cuidadores de pessoas com doença mental: d...

No estágio desenvolvido em contexto de saúde mental e psiquiatria surgiu a oportunidade de realizar atividades de promoção da saúde mental às famílias/cuidadores de pessoas com doença mental, respondendo aos desafios decorrentes da pandemia Covid-19 tal como diz a Norma nº011/2020 (DGS, 2020, p.1) “o impacto na saúde das populações e a velocidade instantânea de transmissão da informação (…), suscitam nas popula...

Environmental pH modulates biofilm formation and matrix composition in Candida ...

Candida species are fungal opportunistic pathogens capable of colonizing and infecting various human anatomical sites, where they have to adapt to distinct niche-specific pH conditions. The aim of this study was to analyse the features of Candida albicans and Candida glabrata biofilms developed under neutral and vaginal acidic (pH 4) conditions. C. albicans produced thicker and more filamentous biofilms under n...

Honey as a strategy to fight Candida tropicalis in mixed-biofilms with Pseudomo...

Fungal contaminations with Candida species are commonly responsible for several infections, especially when associated to bacteria. The therapeutic approach commonly used is being compromised due to microbial resistances of these microorganisms to antimicrobial agents, especially in biofilm. The use of honey as an antimicrobial agent has been emerging as a valuable solution and proving its potential in plankton...

Phytochemical characterization of Borago officinalis L. and Centaurea cyanus L....

The present work details the nutritional and chemical compositions of borage and centaurea, at three flowering stages. Water was the main constituent, followed by total dietary fiber. Both flowers showed statistically different (p < 0.05) nutritional and chemical profiles, although in both, polyunsaturated fatty acids (PUFAs) (mainly linoleic and α-linolenic acids), free sugars (3.9-28.9% dw as fructose, glucos...

The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing ...

The Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...

On the Physical Vapour Deposition (PVD): Evolution of Magnetron Sputtering Proc...

Advanced coatings play an important role in a wide range of industrial applications. These coatings are commonly used in machining tools due to their high hardness and wear resistance, but also can be applied in jewellery and decorative purposes. Deposition techniques have seen a strong evolution as result of the directly related devices, control evolution and software. Several variants have been developed arou...