6 documents found, page 1 of 1
Piezoelectric PVDF nanoparticles for enhanced antimicrobial activity via mechan...
Fernandes, Mariana Isabel Pires; Moreira, Joana; Fernandes, Marta Susana Machado; Zille, Andrea; Silva, C.; Silva, Filipe Samuel; Fernandes, Margarida MThe alarming rise of antimicrobial resistance is a public health issue, driven by the excessive and improper use of antibiotics, which are becoming less effective against an increasing number of microorganisms. There is an urgent need to find alternative antimicrobial strategies that can bypass bacterial resistance mechanisms. Using physical stimuli to sensitize bacteria to antimicrobial action is one step towa...
Acylase-based coatings on sandblasted polydimethylsiloxane-based materials for ...
Silva, Cláudia A.; Moreira, Joana Isabel Machado; Fernandes, Marta Susana Machado; Zille, Andrea; Cardoso, Vanessa Fernandes; Nine, Md JulkerIndwelling medical devices, such as urinary catheters, often experience bacterial colonization, forming biofilms that resist antibiotics and the host's immune defenses through quorum sensing (QS), a chemical communication system. This study explores the development of antimicrobial coatings by immobilizing acylase, a quorum-quenching enzyme, on sandblasted polydimethylsiloxane (PDMS) surfaces. PDMS, commonly us...
Zirconia surface functionalization by laser with antimicrobial nanoparticles fo...
Costa, Daniel Coutinho; Fernandes, Margarida M; Silva, Filipe Samuel; Madeira, Sara Cristina Soares; Carvalho, Óscar Samuel NovaisDental implants are considered the best solution for missing teeth but are sometimes associated with complications such as peri-implantitis, which is caused by bacteria and is characterized by tissue inflammation and bone loss which causes dental implants to fail over time [1]. Metal nanoparticles (NPs) can be a good antibacterial agent to be employed in dental implantology to prevent this pathology [2]. Zircon...
Light therapy on a functionalized zirconia surface with antimicrobial nanoparti...
Costa, Daniel Coutinho; Fernandes, Margarida M; Silva, Filipe Samuel; Madeira, Sara Cristina Soares; Carvalho, Óscar Samuel NovaisLight therapy on a functionalized zirconia surface with antimicrobial nanoparticles for dental applications Dental implants are considered the best solution for missing teeth but are sometimes associated with complications such as peri-implantitis, which is caused by bacteria and is characterized by tissue inflammation and bone loss which causes dental implants to fail over time [1]. Metal nanoparticles (NPs) c...
Designing antimicrobial biomembranes via clustering amino-modified cellulose na...
Carvalho, Estela Marisa Oliveira; Rincón-Iglesias, Mikel; Brito-Pereira, Ricardo; Lizundia, Erlantz; Fernandes, Margarida M; Lanceros-Mendez, S.The continuous rising of infections caused by multidrug-resistant pathogens is becoming a global healthcare concern. Developing new bio-based materials with unique chemical and structural features that allow efficient interaction with bacteria is thus important for fighting this phenomenon. To address this issue, we report an antimicrobial biomaterial that results from clustering local facial amphiphilicity fro...
Smart and multifunctional materials based on electroactive poly(vinylidene fluo...
Costa, Carlos Miguel Silva; Cardoso, Vanessa Fernandes; Martins, Pedro Libânio Abreu; Correia, Daniela Maria Silva; Gonçalves, Renato FerreiraFrom scientific and technological points of view, poly(vinylidene fluoride), PVDF, is one of the most exciting polymers due to its overall physicochemical characteristics. This polymer can crystalize into five crystalline phases and can be processed in the form of films, fibers, membranes, and specific microstructures, being the physical properties controllable over a wide range through appropriate chemical mod...