64 documents found, page 1 of 7

Evidência psicométrica do Humor Styles Questionnaire (HSQ) numa amostra de trab...

O humor tem uma vasta história, nos últimos anos começou a ser alvo de maior atenção devido aos seus benefícios para a saúde e o bem-estar. Trabalhos recentes indicaram que este conceito pode ser uma ferramenta útil no contexto laboral. Porém, na literatura não há registo de uma medida validada para aferir o humor no contexto de trabalho numa amostra de trabalhadores portugueses. O principal objetivo desta inve...

GO TECOLIVE – Efeitos de um composto orgânico na fertilidade do solo e no desen...

Neste estudo, realizado no âmbito do Grupo Operacional “Técnicas e tecnologia para valorização de subprodutos em olivicultura – TECOLIVE” - PDR 2020-101-031764, pretendeu-se testar a eficácia e segurança de um corretivo organico obtido por compostagem na própria exploração e utilizando os recursos existentes, com base em subprodutos do olival e efluentes de atividade pecuária, designadamente folhas e raminhos d...

Potential biological properties of lycopene in a self-emulsifying drug delivery...

In recent years, lycopene has been highlighted due to its antioxidant and anti-inflammatory properties, associated with a beneficial effect on human health. The aim of this study was to advance the studies of antioxidant and anti-inflammatory mechanisms on human keratinocytes cells (HaCaT) of a self-emulsifying drug delivery system (SEDDS) loaded with lycopene purified from red guava (nanoLPG). The characterist...

Patterns and controls on fluvial incision in the lower Douro River (Western Ibe...

The Douro River, is ~900 km long and has a drainage basin of ~97,600 km2, crossing most of the Iberian Peninsula from east to west. The evolution of the Douro system documents an outstanding example of a continental-scale drainage reorganization, reflecting a transition from endorheic to exorheic conditions. By the middle Cretaceous, the passive Western Iberian Margin was tectonically reactivated by an increasi...

Valorização agrícola de subprodutos do olival e do lagar – GO TECOLIVE

No modelo de economia circular, a valorização agrícola dos subprodutos do olival e da indústria de extração de azeite apresenta-se como uma via privilegiada para o seu escoamento contribuindo, assim, para a resolução deste enorme problema que tanto preocupa as empresas do setor - o dar destino adequado a estes subprodutos - com benefícios agronómicos e ambientais A produção de composto orgânico, a partir destes...

Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple...

Triple negative breast cancer (TNBC) is a highly heterogenous disease not sensitive to endocrine or HER2 therapy and standardized treatment regimens are still missing. Therefore, development of novel TNBC treatment approaches is of utmost relevance. Herein, the potential of MAPK/ERK downregulation by RNAi-based therapeutics in a panel of mesenchymal stem-like TNBC cell lines was uncovered. Our data revealed tha...

Exploring silk Sericin for diabetic wounds: an in situ-forming hydrogel to prot...

Chronic wounds are one of the most frequent complications that are associated with diabetes mellitus. The overproduction of reactive oxygen species (ROS) is a key factor in the delayed healing of a chronic wound. In the present work, we develop a novel in situ-forming silk sericin-based hydrogel (SSH) that is produced by a simple methodology using horseradish peroxidase (HRP) crosslinking as an advanced dressin...

Exercise performed during pregnancy positively modulates liver metabolism and p...

Gestational diabetes mellitus (GDM) is associated with a high-risk for metabolic complications in offspring. However, exercise is recognized as a non-pharmacological strategy against metabolic disorders and is recommended in GDM treatment. This study aimed to investigate whether gestational exercise (GE) could modulate maternal high-fat high-sucrose (HFHS) diet-related hepatic metabolic and mitochondrial outcom...

Patterns and controls on fluvial incision in the lower Douro River (Western Ibe...

UAV-based very high resolution point cloud, digital surface model and orthomosa...

Fogo in the Cabo Verde archipelago of western Africa is one of the most prominent and active ocean island volcanoes on Earth, posing an important hazard both to local populations and at a regional level. The last eruption took place between 23 November 2014 and 8 February 2015 in the Chã das Caldeiras area at an elevation close to 1800ĝ€¯ma.s.l. The eruptive episode gave origin to extensive lava flows that almo...