O comprometimento organizacional (CO) envolve a lealdade, o compromisso moral e o desejo de permanecer numa organização. Os objetivos desta investigação são: determinar o nível de CO em enfermeiros das três unidades hospitalares integrantes da Unidade local de Saúde do Nordeste, Portugal; e, comparar o CO e suas dimensões (Afetiva, Calculativa e Normativa) segundo diversos fatores (idade, tipo de contrato, temp...
Os enfermeiros, o grupo profissional mais representativo no sistema de saúde, possuem competências científicas, técnicas e humanas para a prestação de cuidados de enfermagem gerais ao indivíduo, família, grupos e comunidade. O nível de comprometimento organizacional (CO) destes profissionais está intimamente ligado à sua produtividade e à qualidade dos cuidados de saúde prestados. O presente estudo, quantitativ...
Abstract: Introduction: Non-suicidal self-injury (NSSI) is common among college students and is best understood as a self-soothing method for dealing with aversive emotional states. Aims: To analyse the pathway that sustains the association between NSSI, depressive symptomatology, emotion dysregulation and self-criticism in college students. Method: Three hundred eighty-five students (85.2% females) between 18 ...
Introduction: Non-suicidal self-injury (NSSI) is common among college students and is best understood as a self-soothing method for dealing with aversive emotional states. Aims: To analyse the pathway that sustains the association between NSSI, depressive symptomatology, emotion dysregulation and self-criticism in college students. Method: Three hundred eighty-five students (85.2% females) between 18 and 35 yea...
Abstract: Introduction: Non-suicidal self-injury (NSSI) is common among college students and is best understood as a self-soothing method for dealing with aversive emotional states. Aims: To analysethe pathway that sustains the association between NSSI, depressive symptomatology, emotion dysregulation and self-criticism in college students. Method: Three hundred eighty-five students (85.2% females) between 18 a...
Bladder Cancer (BC) is one of the most common cancers, with Non-Muscle Invasive Bladder Cancer (NMIBC) accounting for the majority of its cases. This cancer has a high relapse rate leading to the need of frequent surveillance. BC monitoring entails frequent cystoscopy analyses, an invasive and painful procedure. This work aims to provide the basis to develop non-invasive and patient compliant urine-based tests ...
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Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically incurable. Defining the genetic basis of NOA has proven chal lenging, and the most advanced classification of NOA subforms is not based on genetics, but simple description of testis histology. In this study, we exome sequenced over 1000 clinically diagnosed NOA cases and identified a plausible recessive Mendelian cause i...
De novo mutations are known to play a prominent role in sporadic disorders with reduced fitness. We hypothesize that de novo mutations play an important role in severe male infertility and explain a portion of the genetic causes of this understudied disorder. To test this hypothesis, we utilize trio-based exome sequencing in a cohort of 185 infertile males and their unaffected parents. Following a systematic an...
Study question: What is the load, distribution and added clinical value of secondary findings (SFs) identified in exome sequencing (ES) of patients with non-obstructive azoospermia (NOA)? Summary answer: One in 28 NOA cases carried an identifiable, medically actionable SF. What is known already: In addition to molecular diagnostics, ES allows assessment of clinically actionable disease-related gene variants tha...