62 documents found, page 1 of 7
Assessment of Fluid Status in Dialysis: Clinical Importance and Diagnostic Tools
Damas, J; Fernandes, VFluid status is crucial for dialysis patients. Volume overload is a major cardiovascular risk factor. Nevertheless, volume depletion is associated with myocardial stunning and cerebral ischaemia. For decades, many diagnostic tools have been proposed for increased accuracy in evaluation of volemia, considering that clinical assessment is unreliable. Lung ultrasound and bioimpedance analysis emerged as the most u...
Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inf...
Pedro, N; Fernandes, V; Cavadas, B; Guimarães, JT; Barros, H; Tavares, M; Pereira, LField epidemiology and viral sequencing provide a comprehensive characterization of transmission chains and allow a better identification of superspreading events. However, very few examples have been presented to date during the COVID-19 pandemic. We studied the first COVID-19 cluster detected in Portugal (59 individuals involved amongst extended family and work environments), following the return of four rela...
Dynamics of a Dual SARS-CoV-2 Lineage Co-Infection on a Prolonged Viral Sheddin...
Pedro, N; Silva, CN; Magalhães, AC; Cavadas, B; Rocha, AM; Moreira, AC; Gomes, MS; Silva, D; Sobrinho-Simões, J; Ramos, A; Cardoso, MJ; Filipe, RA few molecularly proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases of symptomatic reinfection are currently known worldwide, with a resolved first infection followed by a second infection after a 48 to 142-day intervening period. We report a multiple-component study of a clinically severe and prolonged viral shedding coronavirus disease 2019 (COVID-19) case in a 17-year-old Portuguese f...
Projecting Ancient Ancestry in Modern-Day Arabians and Iranians: A Key Role of ...
Ferreira, JC; Alshamali, F; Montinaro, F; Cavadas, B; Torroni, A; Pereira, L; Raveane, A; Fernandes, VThe Arabian Peninsula is strategic for investigations centered on the early structuring of modern humans in the wake of the out-of-Africa migration. Despite its poor climatic conditions for the recovery of ancient human DNA evidence, the availability of both genomic data from neighboring ancient specimens and informative statistical tools allow modeling the ancestry of local modern populations. We applied this ...
Dynamics of a dual sars-cov-2 lineage co-infection on a prolonged viral sheddin...
Pedro, N; Silva, CN; Magalhães, AC; Cavadas, B; Rocha, AM; Moreira, AC; Gomes, MS; Silva, D; Sobrinho-Simões, J; Ramos, A; Cardoso, MJ; Filipe, RA few molecularly proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases of symptomatic reinfection are currently known worldwide, with a resolved first infection followed by a second infection after a 48 to 142-day intervening period. We report a multiplecomponent study of a clinically severe and prolonged viral shedding coronavirus disease 2019 (COVID-19) case in a 17-year-old Portuguese fe...
Polidocanol Foam Injected at High Doses with Intravenous Needle: The (Almost) P...
Fernandes, V; Fonseca, JBACKGROUND AND AIMS: Hemorrhoid disorders are common. This study aimed to assess the efficacy and safety of polidocanol foam injected at high doses with intravenous needle for the treatment of symptomatic internal hemorrhoids that prolapse or bleed. METHODS: We evaluated 2,000 consecutive patients with prolapsed hemorrhoids (grades II/III/IV) recruited over 6 years. Foam injection was performed in one to four s...
Evidence of Austronesian Genetic Lineages in East Africa and South Arabia: Comp...
Brucato, N; Fernandes, V; Kusuma, P; Cerny, V; Mulligan, CJ; Soares, P; Rito, T; Besse, C; Boland, A; Deleuze, JF; Cox, MP; Sudoyo, H; Stoneking, MPublished by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. The Austronesian dispersal across the Indonesian Ocean to Madagascar and the Comoros has been well documented, but in an unexplained anomaly, few to no traces have been found of the Austronesian expansion in East Africa or the Arabian Peninsula. To revisit this peculiarity,we surveyedtheWesternIndianOcean rimpopul...
Universal vs. risk-factor-based screening for gestational diabetes-an analysis ...
Matta-Coelho, C; Monteiro, AM; Fernandes, V; Pereira, ML; Souto, SBPURPOSE: The criteria to screen for Gestational Diabetes Mellitus are not internationally consensual. In opposition to the universal screening performed in Portugal, certain countries advocate a risk-factor-based screening. We aim to compare obstetric and neonatal outcomes in pregnant women with and without risk factors treated for Gestational Diabetes Mellitus. METHODS: Retrospective and multicentric study of ...
Iron Deficiency and Obesity - Are we Diagnosing with Appropriate Indicators?
Monteiro, AM; Fernandes, V; Matta-Coelho, C; Paredes, Sílvia; Pereira, ML; Marques, O; Alves, MINTRODUCTION: We aim to define the iron deficiency prevalence and eventual differences between obese patients with and without metabolic syndrome. MATERIAL AND METHODS: Analysis of patients evaluated at multidisciplinary consultation of obesity in our institution between 2013 and 2015 (n = 260). Iron deficiency: ferritin levels < 15 ng/mL. EXCLUSION CRITERIA: prior bariatric surgery; lack of ferritin or hemoglo...
Hipotiroidismo Subclínico no Idoso
Macedo Silva, S; Carvalho, A; Lopes-Pereira, M; Fernandes, VSubclinical hypothyroidism, defined as an increase of thyroid stimulating hormone levels with normal levels of thyroid hormones, could have a multiorgan impact. There seem to be differences in the elderly (over 65 years of age) which indicate that there should be a different approach in terms of diagnosis and the treatment.