© 2020 Wiley Periodicals LLC.; Bullous pemphigoid (BP) is the most common autoimmune blistering disease. High potency topical and/or systemic corticosteroids as well as immunosuppressants are the current mainstay of treatment. However, long-term steroid therapy and systemic immunosuppression may result in significant morbidity and mortality. Contribution of IgE to BP pathogenesis remains under investigation, bu...
Introduction: Cellulitis and erysipelas represent the most frequent cause of hospitalization in the dermatology department of Santa Maria Hospital in Lisbon, Portugal. The aim of this study was to investigate whether patient demographics, comorbidities, previous episodes of cellulitis/erysipelas, the presence of complications, laboratory markers at admission, microbial isolation or previous use of antibiotics, ...
Copyright © Ordem dos Médicos 2019.; Introduction: Cellulitis and erysipelas represent the most frequent cause of hospitalization in the dermatology department of Santa Maria Hospital in Lisbon, Portugal. The aim of this study was to investigate whether patient demographics, comorbidities, previous episodes of cellulitis/erysipelas, the presence of complications, laboratory markers at admission, microbial isola...
Background: Chronic urticaria is defined as the appearance of urticarial lesions and/or angioedema during a period of more than six weeks. We aimed at developing the Portuguese version of the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) and at testing its reliability and the content, construct and criterion validity. Methods: The forward-backward approach to a linguistic equivalence was followed, a...
The effects of immunodepression on several disease states have constituted an important area of research, leading to the identification of relevant associations between immunodepression and a vast set of comorbidities, including infectious diseases, cardiovascular diseases and cancer. Research on the effects of immunodepression has mostly been conducted in individuals under immunodepression by the human immunod...
Copyright © Ordem dos Médicos 2017; The effects of immunodepression on several disease states have constituted an important area of research, leading to the identification of relevant associations between immunodepression and a vast set of comorbidities, including infectious diseases, cardiovascular diseases and cancer. Research on the effects of immunodepression has mostly been conducted in individuals under i...
© 2017 by the American Academy of Dermatology, Inc. Published by Elsevier, Inc. This is an open access article under the CC BY- NC-ND license (http://creativecommons.org/licenses/by-nc-nd/ 4.0/).; A 19-year-old white woman was referred to our outpatient dermatology clinic with an undiagnosed skin eruption since early childhood. She was born from normal delivery after an uneventful pregnancy from healthy noncons...
A cutaneous collision or contiguous tumor occurs when two or more cutaneous tumors coexist in a single lesion. These tumors usually have misleading clinical and histological presentations, making them a diagnostic challenge. Although several different combinations of collisions have been described we report an unusual case of a cutaneous collision tumour on the back of the patient involving an intradermal naevu...
The concept of field cancerization, described in various types of cancer, has been intensely studied in skin cancer. It can be defined as the process in which the cells in a tissue or organ are transformed, with genetic modifications, but with normal clinical and histologic features, prior to neoplastic development or coexisting with malignant cells, independently of clonality. Applying this concept to clinical...
Dermatomyositis is an idiopathic inflammatory myopathy with cutaneous involvement. In patients over 60 years may be associated with underlying neoplasms. The most frequently involved are the lung, ovary and digestive system. The Struma ovarii is a rare ovarian tumor, which is defined by the presence of thyroid tissue, associated to a teratoma or a mucinous cystadenoma. There are benign and malignant histologica...