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Association between col1a2 Polymorphism and the Occurrence of Pelvic Organ Prol...
Rosa,Josyandra Paula de Freitas; Haddad,Raphael Federicci; Maeda,Fabiana Garcia Reis; Souto,Ricardo Peres; Fernandes,Cesar Eduardo; Oliveira,Emerson deAbstract Objective To evaluate the rs42524 polymorphism of the procollagen type I alpha (α) 2 (COL1A2) gene as a factor related to the development of pelvic organ prolapse (POP) in Brazilian women. Methods The present study involved 112 women with POP stages III and IV (case group) and 180 women with POP stages zero and I (control group). Other clinical data were obtained by interviewing the patients about thei...
Personality Traits of Postmenopausal Women with Sexual Dysfunction
Caires,Cristiano Santos de; Steiner,Marcelo Luis; Pompei,Luciano de Melo; Strufaldi,Rodolfo; Fernandes,Cesar EduardoAbstract Objective The aim of the present study is to identify the association between personality traits of postmenopausal women and the occurrence of sexual dysfunction. Methods A total of 43 postmenopausal women were evaluated according to their self-perception of the quality of their sexual life. They answered the following questionnaires: Sociodemographic Profile Questionnaire, Female Sexual Function Index...
The Influence of CYP3A4 Polymorphism in Sex Steroids as a Risk Factor for Breas...
Veiga,Melissa Gonzalez; Felizi,Rogério Tadeu; Reis,Dayane Guerino; Carelli Filho,Ivo; Fernandes,Cesar Eduardo; Souto,Ricardo Peres do; Oliveira,EmersonAbstract Objective Epidemiological studies have shown evidence of the effect of sex hormones in the pathogenesis of breast cancer, and have suggested a relationship of the disease with variations in genes involved in estrogen synthesis and/or metabolism. The aim of the present study was to evaluate the association between the CYP3A4*1B gene polymorphism (rs2740574) and the risk of developing breast cancer. Meth...
Evaluation of Quality of life, Physical Activity and Nutritional Profile of Pos...
Delchiaro,Adriele; Oliveira,Flávia de Jesus; Bonacordi,Camila Lopez; Chedid,Bruna Libanori; Annicchino,Giuliana; Fernandes,Cesar EduardoAbstract Introduction Vitamin D deficiency is associated with various diseases. Prevalent in Brazil, it can result from inadequate lifestyle habits. Objective To demonstrate that postmenopausal women with vitamin D deficiency have worse quality of health, expressed as worse quality of life, lower levels of physical activity, and worse nutritional profile. Methods Postmenopausal women answered questionnaires abo...
Brazilian guidelines for the diagnosis and treatment of postmenopausal osteopor...
Radominski,Sebastião Cézar; Bernardo,Wanderley; Paula,Ana Patrícia de; Albergaria,Ben-Hur; Moreira,Caio; Fernandes,Cesar Eduardo; Castro,Charlles H.M.Abstract Osteoporosis is the leading cause of fractures in the population older than 50 years. This silent disease affects primarily postmenopausal women and the elderly, and the morbidity and mortality rates are high. The main goal of treating osteoporosis is the prevention of fractures. The identification of populations at risk through early diagnosis and treatment is essential. The last Brazilian guideline f...