2 documents found, page 1 of 1
Managing intrathecal administration of nusinersen in adolescents and adults wit...
Mendonça,Rodrigo de Holanda; Fernandes,Hermann dos Santos; Pinto,Rafael Barbéro Schimmelpfeng; Matsui Júnior,Ciro; Polido,Graziela JorgeABSTRACT Background: Spinal muscular atrophy (SMA) is a neurodegenerative disease of lower motor neurons associated with frequent occurrence of spinal deformity. Nusinersen is an antisense oligonucleotide that increases SMN protein level and is administrated by frequent intrathecal lumbar injections. Thus, spinal deformities and previous spinal surgery are important challenges for drug delivery in SMA. Objectiv...
Lumbar erector spinae plane block for total hip arthroplasty analgesia. Case re...
Azevedo,Artur Salgado de; Fernandes,Hermann dos Santos; Cunha Júnior,Waldir; Hamaji,Adilson; Ashmawi,Hazem AdelABSTRACT BACKGROUND AND OBJECTIVES: Total hip replacement surgeries may result in intense postoperative pain. There are many analgesia techniques available in clinical practice and lumbar erector spine plane (LESP) block may be an option of an effective technique with milder adverse effects and easier execution. CASE REPORT: Female patient, 23-year-old, allergic to morphine and tramadol, underwent a total left ...