37 documents found, page 1 of 4
Quality Control for Lignin and Gelatin Microcapsules Loaded with Orange Essenti...
Aguiar,Maria Clara S.; Denadae,Bárbara E.; Silva,Maria Fátima G. F.; Fernandes,João B.; Bittencourt,Paulo R. S.; Scremin,Fernando R.; Forim,Moacir R.Sustainable natural product-based microstructured systems and biopolymers are strong candidates for use in crop protection. Lignin and gelatin microcapsules loaded with orange essential oil were developed with spray-drying in order to enhance its potential. We evaluated the microparticle controlled release mechanisms, biological effects, structural and thermal properties. A quantitative method using headspace-g...
Valorization of Hesperidin from Citrus Residues: Evaluation of Microwave-Assist...
Silva,Danielle F. da; Bomfim,João P. A.; Marchi,Rafael C.; Amaral,Jéssica C.; Pinto,Luciano S.; Carlos,Rose M.; Ferreira,Antonio G.; Forim,Moacir R.The aim of the current study was the valorization of hesperidin, the dominant flavonoid in citrus processing waste, by microwave-assisted synthesis of hesperidin-Mg complex, improving its antioxidant activity and insecticidal potential. Here we show, for the first time, that microwave-assisted synthesis of [Mg(hesp)2(phen)]OAc (1) (hesp: hesperidin, phen: phenanthroline) improve the reaction rate and yield. The...
Evaluation of Lignins of Trunk and Roots from Citrus sinensis L. Osbeck: A Larg...
Porto,Deyvid S.; Forim,Moacir R.; Costa,Eveline S.; Fernandes,João B.; Silva,Maria F. G. F. daCitrus biomass is a source of biobased products and presents extensive chemical diversity. Among the structural macromolecules, lignins have been used in resins, bioplastics, and nanoencapsulation. Brazil has a large source of lignins, which are orange trees removed from groves that need to be renewed. However, the knowledge about these lignins is limited and little explored. Thus, this work aimed to evaluate t...
INSECTICIDAL AND FUNGICIDAL ACTIVITY OF A MAGNESIUM COMPOUND CONTAINING ISOVANI...
Silva,Eldevan S.; Marchi,Rafael C.; Matos,Carla Sthefane P.; Silva,Maria Fátima G. F.; Fernandes,João B.; Bueno,Odair C.; Carlos,Rose M.Pesticides offer a simple, cost-effective solution to ensure food supplies for a growing world population. However, their environmental performance needs improvement if pesticides are to continue contributing importantly. This study explores the insecticidal potential of a magnesium (II) metal complex containing 1,10-phenanthroline and isovanillic acid (MgPhenIso) against leaf-cutting ant (Atta sexdens rubropil...
New Synthetic Quinolines as Cathepsin K Inhibitors
Silva,Taynara L.; Bartolomeu,Aloisio de A.; Jesus,Hugo C. R. de; Oliveira,Kleber T. de; Fernandes,João B.; Brömme,Dieter; Vieira,Paulo C.Cathepsin K is a papain-like cysteine protease and is responsible for collagen degradation in bone tissue and thus represents an important target for the development of new therapies for treating diseases such as osteoporosis. Quinolines are an important class of heterocyclic molecular leads with a great pharmacological potential and represent a relevant scaffold to explore the chemical space of cathepsin K (Ca...
New Limonoids from Dictyoloma vandellianum and Sohnreyia excelsa: Chemosystemat...
Sartor,Claudenice F. P.; Lima,Maria da Paz; Silva,Maria Fátima G. F. da; Fernandes,João B.; Forim,Moacir R.; Pirani,José R.Molecular phylogenetic studies separated and united a group of genera that constituted the Spathelia-Ptaeroxylon clade, in which Dictyoloma and Sohnreyia have been included. Our taxonomic interest in the Dictyoloma vandellianum and Sohnreyia excelsa stimulated an investigation of both species searching for limonoids. Leaves from D. vandellianum afforded the new limonoid 1,2-dihydro-1α-hydroxy-8,30-epoxy-cneorin...
An Environmentally Friendly Procedure to Obtain Flavonoids from Brazilian Citru...
Bellete,Barbara S.; Ramin,Luize Z.; Porto,Deyvid; Ribeiro,Alany I.; Forim,Moacir R.; Zuin,Vânia G.; Fernandes,João B.; Silva,Maria Fátima G. F.Currently, most food waste is used as animal feed and this process does not take advantage of the available chemical composition. A Brazilian example is the citrus fruit processing wastes (CFPW), which have begun to draw attention due to their biological importance. In order to access the main compounds of this matrix, an efficient and environmentally friendly procedure was tested. From this extract, flavonoids...
Use of Lignins from Sugarcane Bagasse for Assembling Microparticles Loaded with...
Costa,Eveline S.; Perlatti,Bruno; Silva,Everton M. da; Matos,Andreia P.; Silva,Maria Fátima G. F. da; Fernandes,João B.; Zuin,Vânia G.Microcapsules of sugarcane bagasse lignin loaded with organic extracts of neem (Azadirachta indica) were prepared and evaluated as potential bioinsecticides. Lignins were extracted and modified by oxidation and acetylation reactions providing different biopolymers. Afterwards, they were characterized through several analytical techniques. The formulations were initially prepared as colloidal suspension of ligni...
Isolation of Tiliroside from Spiranthera odoratissima as Inhibitor of Trypanoso...
Cornelio,Vivian E.; Maluf,Fernando V.; Fernandes,João B.; Silva,Maria Fátima G. F. da; Oliva,Glaucius; Guido,Rafael V. C.; Vieira,Paulo C.Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme involved in the Trypanosoma cruzi glycolytic pathway, parasite that causes Chagas' disease. There are only few drugs available to treat this disease, most of which present strong side effects. Natural products constitute a prime source for the discovery of new scaffolds potentially useful for the treatment of several diseases, including Chagas' di...
Application of a Quantitative HPLC-ESI-MS/MS Method for Flavonoids in Different...
Perlatti,Bruno; Fernandes,João B.; Silva,Maria F. G. F.; Ardila,Jorge A.; Carneiro,Renato L.; Souza,Bruno H. S.; Costa,Eduardo N.; Eduardo,Wellington I.Plant flavonoids have been increasingly studied for its importance in plant metabolism, inter-species interactions and human health-promoting effects. Each botanical species has a distinct flavonoid profile, and as such, this work aimed to develop and apply a high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) method to quantify specific flavonoids...