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An antisense transcript mediates MALAT1 response in human breast cancer
Gomes, Carla Pereira; Nobrega-Pereira, Sandrina; Domingues Silva, Ana Beatriz; Rebelo, Kenny; Alves-Vale, Catarina; Marinho, Sérgio; Carvalho, TâniaBackground: Long non-coding RNAs (lncRNAs) represent a substantial portion of the human transcriptome. LncRNAs present a very stringent cell-type/tissue specificity being potential candidates for therapeutical applications during aging and disease. As example, targeting of MALAT1, a highly conserved lncRNA originally identified in metastatic non-small cell lung cancer, has shown promising results in cancer regr...
Date: 2019
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Origin: Repositório da Universidade de Lisboa