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Real-World Experience with Avacopan in ANCA-Associated Vasculitis in Portugal

Oliveira Correia, Sofia; Laranjinha, Ivo; Nogueira, Estela; Cunha, Anita; Tenazinha, Catarina; Pinto, Helena; Ferreira, Inês; Fernandes Serodio, João

Introduction: Avacopan, a selective C5a receptor inhibitor, has emerged as a potential corticosteroid-sparing treatment in ANCA-associated vasculitis (AAV). This study aims to evaluate its real-world efficacy and safety in Portuguese patients with active AAV. Methods: We conducted a multicenter retrospective analysis of 15 adult patients with newly diagnosed or relapsing AAV treated with avacopan across nine ac...


Etiology, Treatment and Prognosis of Acute Pericarditis

Fernandes Serodio, João; Trindade, Miguel; Achega, Miguel; Faria, Daniel; Maurício, Joana; Batista, Frederico; Favas, Catarina; Delgado Alves, José

Introduction: Acute pericarditis is a common inflammatory condition of the pericardium usually assumed to be viral or idiopathic. Despite recent treatment improvements, information is scarce regarding etiology and prognosis. Our aim was to determine the incidence of pericarditis with a known etiology and assess clinical prognostic predictors. Material and Methods: A clinical retrospective analysis of hospitaliz...


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