Background Carboplatin is a renally excreted antineoplastic drug associated with myelotoxic effects. Doses are calculated according to the Calvert formula. The change from Cockcroft-Gault (CG) to the race-free Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) may have an impact on doses. The aim of the study was to evaluate the difference in carboplatin doses based on estimated glomerular filtration r...
Introduction: Poor access to community pharmacies has been associated with restricted accessibility to medicines. We aimed to compare the geographic distribution of community pharmacies and healthcare centers (HCCs) and identify sociodemographic variables associated with geographical discrepancies at the municipal level in Portugal. Methods: Data on HCC, physicians, pharmacies, and pharmacists were collected at...
Introduction: Medical Subject Headings (MeSH) are the controlled vocabulary used by the National Library of Medicine (NLM) to index articles covered by MEDLINE. Objective: Evaluate the consistency of MeSH assignment using a test-retest analysis of articles published multiple times. Methods: Three sets of articles that had been published multiple times were selected: Vancouver Group articles, CONSORT Statement a...
In the Brazilian Health System (SUS), drugs covered by the Specialized Pharmaceuti-cal Scheme (CEAF) receive federal funding and can be procured either centrally (Group 1A) or by individual states (Federal Units -UF) (Group 1B). Unlike other countries where national pro-curement prices are negotiated centrally by the government, public procurement in Brazil follows a public auction procedure, potentially result...
Objectives To evaluate human-based Medical Subject Headings (MeSH) allocation in articles about 'patient simulation'-a technique that mimics real-life patient scenarios with controlled patient responses.Methods A validation set of articles indexed before the Medical Text Indexer-Auto implementation (in 2019) was created with 150 combinations potentially referring to 'patient simulation'. Articles were classifie...
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Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clini...