4 documents found, page 1 of 1
Epigenomics in Hurthle Cell Neoplasms: Filling in the Gaps Towards Clinical App...
Canberk, S; Lima, AR; Pinto, M; Soares, P; Máximo, VIt has been widely described that cancer genomes have frequent alterations to the epigenome, including epigenetic silencing of various tumor suppressor genes with functions in almost all cancer-relevant signalling pathways, such as apoptosis, cell proliferation, cell migration and DNA repair. Epigenetic alterations comprise DNA methylation, histone modification, and microRNAs dysregulated expression and they pl...
Translational Potential of Epigenetic-Based Markers on Fine-Needle Aspiration T...
Canberk, S; Lima, AR; Pinto, M; Máximo, VThe awareness of epigenetic alterations leading to neoplasia attracted the attention of researchers toward its potential use in the management of cancer, from diagnosis to prognosis and prediction of response to therapies. Our group has focused its attention on the epigenomics of thyroid neoplasms. Although most of the epigenetic studies have been applied on histological samples, the fact is that cytology, thro...
Dynamin-related protein 1 at the crossroads of cancer
Lima, AR; Santos, L; Correia, M; Soares, P; Sobrinho-Simões, M; Melo, M; Máximo, VMitochondrial dynamics are known to have an important role in so-called age-related diseases, including cancer. Mitochondria is an organelle involved in many key cellular functions and responds to physiologic or stress stimuli by adapting its structure and function. Perhaps the most important structural changes involve mitochondrial dynamics (fission and fusion), which occur in normal cells as well as in cells ...
Tamanho da Partícula do Milho e Forma Física da Ração e Seus Efeitos Sobre o De...
Dahlke, F [UNESP]; Ribeiro, AML; Kessler, AM; Lima, ARSubmitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:08:07Z No. of bitstreams: 0; Made available in DSpace on 2013-08-22T19:08:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2001-12-01; Made available in DSpace on 2013-09-30T20:13:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2001-12-01; Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20...