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Immunohistochemistry quantification by a digital computer-assisted method compa...

Matos, Leandro Luongo de; Stabenow, Elaine; Tavares, Marcos Roberto; Ferraz, Alberto Rosseti; Capelozzi, Vera Luiza; Pinhal, Maria Aparecida da Silva

PURPOSE: To compare immunostaining quantification obtained by a digital computer-assisted method with the well-established semiquantitative analysis. METHODS: Cytoplasmic staining of galectin-3 was obtained by standard immunohistochemical reactions in 25 cases of well-differentiated thyroid carcinoma. The expression index that associates the conventional area fraction of labeled cells with the immunostaining in...

Date: 2006   |   Origin: Oasisbr

Angiogenesis as an indicator of metastatic potential in papillary thyroid carci...

Stabenow, Elaine; Tavares, Marcos Roberto; Ab'Saber, Alexandre Muxfeldt; Parra-Cuentas, Edwin Roger; Matos, Leandro Luongo de; Eher, Esmeralda Miristene

Angiogenesis is new blood vessel formation, a process that can lead to tumor development. Microvessel count has been correlated to metastasis in some neoplasias. PURPOSE: To determine if measurement of microvessel density is useful in predicting metastasis to the cervical lymph node and prognosis in patients with papillary thyroid carcinoma. METHODS: A retrospective analysis was performed in 30 patients that ha...

Date: 2005   |   Origin: Oasisbr

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