2 documents found, page 1 of 1
Toxicogenetic profile of rats treated with aqueous extract from Morinda citrifo...
Moraes, Germano Pinho de; Alencar, Marcus Vinícius Oliveira Barros de; Islam, Torequl; Araújo, Lidiane da Silva; Gomes, Débora Cássia VieiraMorinda citrifolia ( (Family: Rubiaceae) ) is extensive ly use d in traditional med icine due to its anti - inflammatory, antimicrobial, antitumoral , and anti - hypertensive act ivities . However, t here is no substantial data about hepatotoxic and toxicogenetic effects . This study evaluated bioch emical changes and hepatotoxic, genotoxic , and mu tagenic effects of aqueous extract of the fruit of M. citrifol...
Cytogenotoxic and oxidative status evaluation of Morinda citrifolia
Moraes, Germano Pinho de; Alencar, Marcus Vinícius Oliveira Barros de; Islam, Torequl; Araújo, Lidiane da Silva; Sobral, André Luiz PinhoCancer is one of the most leading causes of death worldwide. Morinda citrifolia was reported to have antitumor effects. Cisplatin (CDDP), Doxorubicin (DOX) and Cyclophosphamid (CPA) are the known effective chemotherapeutics, despite of having several side effects. This study evaluated antitumoral and oxidative effects of the aqueous extract of the fruit of M. critrifolia (AEMC) (15, 30, 60 and 120 µg/mL) in com...