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Brazilian registry for the elimination of hepatitis C in dialysis units: a call...

Moura-Neto,José A.; Ferraz,Maria Lúcia Gomes; Bittencourt,Paulo Lisboa; Vieira Neto,Osvaldo Merege

Abstract Infection by the hepatitis C virus is more prevalent in patients on dialysis than in the general population in Brazil, and has been associated with worse outcomes. Current therapy for hepatitis C is highly effective, safe, and widely available in Brazil, with coverage provided to dialysis patients with chronic kidney disease, which makes the elimination of hepatitis C a viable target. The Brazilian Soc...

Date: 2021   |   Origin: Oasisbr

Disease burden of chronic hepatitis C in Brazil

Ferreira,Paulo Roberto Abrão; Brandão-Mello,Carlos Eduardo; Estes,Chris; Gonçales Júnior,Fernando Lopes; Coelho,Henrique Sérgio Moraes; Razavi,Homie

Background: Hepatitis C virus infection is a major cause of cirrhosis; hepatocellular carcinoma; and liver transplantation. The aim of this study was to estimate hepatitis C virus disease progression and the burden of disease from a nationwide perspective.Methods: Using a model developed to forecast hepatitis C virus disease progression and the number of cases at each stage of liver disease; hepatitis C virus-i...

Date: 2015   |   Origin: Oasisbr

Weight-based combination therapy with peginterferon alpha-2b and ribavirin for ...

Gonçales Jr.,Fernando Lopes; Vigani,Aline; Gonçales,Neiva; Barone,Antonio Alci; Araújo,Evaldo; Focaccia,Roberto; Oliveira,Umbeliana

Combination therapy with pegylated interferon and ribavirin is considered the new standard therapy for naïve patients with chronic hepatitis C. We evaluated the efficacy and safety of treatment with weight-based peginterferon alpha-2b (1.5 mg/kg per week) plus ribavirin (800-1,200 mg/day) for 48 weeks in naïve, relapser and non-responder (to previous treatment with interferon plus ribavirin) patients with chron...

Date: 2006   |   Origin: Oasisbr

Epidemiology of acute hepatitis B in a university hospital in São Paulo, Brazil...

Ferraz,Maria Lúcia Gomes; Yoradjian,Alessandra; Barbieri,Andrea; Figueiredo,Virginia; Lopes Neto,Edmundo; Cruz,Cibele Nascimento; Silva,Antonio Eduardo

CONTEXT: HBV infection is endemic in Brazil and acute HBV infection is still a common disease. OBJECTIVE: To analyze incidence, risk factors and evolution of acute HBV infection. SETTING: University Hospital. PATIENTS: 357 patients with acute HBV infection, comparing two periods: 1985-1989 vs. 1990-1994. RESULTS: The overall incidence declined from 50 new cases/year in 1985-89 (30% of all cases) to 25 new cases...

Date: 1998   |   Origin: Oasisbr

Prevalência dos marcadores sorológicos dos vírus da hepatite B e D em crianças ...

Azevedo,Ramiro Anthero; Silva,Antonio Eduardo; Ferraz,Maria Lúcia Gomes; Marcopito,Luiz Francisco; Baruzzi,Roberto Geraldo

O Parque Indígena do Xingu (PIX) está localizado no estado do Mato Grosso, na região de transição de cenado ao sul e da floresta Amazônica ao norte. Dados de literatura mostram que a população adulta apresenta elevada prevalência de marcadores do vírus da hepatite B (HBV). O presente estudo visa determinar a prevalência dos marcadores do HBV e do HDV na população indígena do PIX de zero a 14 anos, e investigar ...

Date: 1996   |   Origin: Oasisbr

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