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Ageing affects the CD4+ T cell polarization and mucosal tropism induced by TLR2...

Zúquete, Sara; Ferreira, Mariana; Delgado, Inês L.S.; Rosa, Maria Teresa; Mendes, Ana Catarina; Santos, Dulce; Nolasco, Sofia; Graca, Luis

Funding was also provided by Fundaci\u00F3n la Caixa through the project HR22-00741. Publisher Copyright: © The Author(s) 2025. Published by Oxford University Press on behalf of Society for Leukocyte Biology.; Toll-like receptor (TLR)2 activation induces aldehyde dehydrogenase enzymes in nonmucosal dendritic cells (DCs) enabling them to metabolize vitamin A into all-trans retinoic acid, which induces the expres...


Optimization of Nanoencapsulation of Codium tomentosum Extract and Its Potentia...

Costa, Micaela; Soares, Cristina; Silva, Aurora; Barroso, Maria Fátima; Simões, Pedro; Ferreira, Mariana; Gameiro, Paula; Grosso, Clara

Funding Information: This work was financed by FEDER—Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020—Operacional Programme for Competitiveness and Internationalisation (POCI), and by Portuguese funds through FCT—Fundação para a Ciência e a Tecnologia in the framework of the project POCI-01-0145-FEDER-030240—PTDC/OCE-ETA/30240/2017—SilverBrain—From Sea to Brain: Green Neuroprotective Ext...


Epidemic intelligence threat reporting profile in Portugal during the COVID-19

Peixoto, Vasco Ricoca; Grau-Pujol, Berta; Ourique, Matilde; Lourenço Da Silva, Renato; Ferreira, Mariana; Firme, Ana; Sentís, Alexis; Vasconcelos, Paula

Publisher Copyright: © 2024 The Author(s). Published by S. Karger AG, Basel on behalf of NOVA National School of Public Health.; Background: Epidemic intelligence (EI) ensures early detection, assessment, and communication of public health threats. Threat reporting defines priorities and mobilize resources for surveillance, prevention, and control. In Portugal, the Directorate-General of Health (DGS) is respons...


Combined TLR2/TLR4 activation equip non-mucosal dendritic cells to prime Th1 ce...

Zúquete, Sara; Ferreira, Mariana; Delgado, Inês L.S.; Gazalle, Paula; Andaluz, Stephanie; Rosa, Maria Teresa; Mendes, Ana Catarina; Santos, Dulce

Funding Information: This work was funded by Fundação para a Ciência e a Tecnologia (FCT; Portugal) through the projects grants PTDC/CVT-CVT/31840/2017, PTDC/CVT-CVT/ 4599/2021, 2022.04903.PTDC, LA/P/0059/2020 (AL4AnimalS– Associate Laboratory for Animal and Veterinary Sciences), and UID/CVT/00276/2019 and UIDB/00276/2020 (CIISA– Center for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medi...


Unlocking the potential of snake venom-based molecules against the malaria, Cha...

Almeida, José Rafael; Gomes, Ana S. M.; Mendes, Bruno; Aguiar, Luísa; Ferreira, Mariana; Brioschi, Mariana Borges Costa; Duarte, Denise

Funding Information: This work received financial support from PT national funds ( FCT/MCTES , Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through the project CIRCNA/BRB/0281/2019 . Funding Information: This work received financial support from PT national funds (FCT/MCTES, Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Super...


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