Introduction: Pectus excavatum (PE) is the most common congenital chest wall deformity, with an incidence of 1 in 400 births. Surgical approaches vary depending on the severity of the condition. Recently, the taulinoplasty approach - "Pectus Up®" - was described as an alternative to lift the sternum through external traction, avoiding invading the mediastinum or pleural cavity. We describe our progressively mod...
O Instituto Politécnico de Leiria está comprometido com a promoção de estilos de vida saudável e ativa na comunidade académica, em alinhamento com a definição de Saúde da Organização Mundial de Saúde (OMS). No âmbito do programa Healthy Campus, a saúde, o bem-estar e os estilos de vida saudáveis são preocupações cada vez mais presentes na nossa Instituição, pelo que solicitámos a colaboração de todos os estudan...
Funding Information: The institutions are funded by Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia/Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020), MOSTMICRO-ITQB (UIDB/04612/2020 and UIDP/04612/2020), and the Associated Laboratory LS4FUTURE (LA/P/0087/2020). This study was supported by a Terr...
Background: Anabolic androgenic steroids (AAS) are synthetic compounds with a chemical structure similar to testosterone. Bodybuilders frequently use them to increase muscle mass, and strength, and reduce body fat. However, AAS can also have adverse effects on health, including alterations in glucose and insulin levels. Aims: This systematic literature review aimed to collect and critically analyze studies that...
It is now indisputable the big role that mass media plays in a society in constant change. Starting from the offline realm, where everything was different, technological evolution has profoundly altered the way sports events are transmitted and discussed. This transformation has not only increased the accessibility and visibility of sports but also challenged the boundaries between the public and the private, b...
Gender dysphoria is defined as a condition characterized by mental suffering associated with the incongruence between one’s experienced gender and their birth-assigned sex. Gender as a construct and gender dysphoria as a condition in need of multidisciplinary intervention have developed as swiftly as their visibility in society, making it mandatory to promote the literacy and education of all healthcare profess...
Testosterone (TE) is an anabolic androgenic steroid (AAS) that promotes muscle growth and the maintenance of secondary sexual characteristics. Due to its aesthetic benefits, AASs have become popular in sports, typically administered orally or intramuscularly, with doses up to 100 times higher than the therapeutic dose. A therapeutic dose is safe and sufficient for the desired effect, while a supraphysiological ...
Although positive childhood experiences (PCEs) may serve as protective factors against the negative consequences of childhood adversity, they have been less extensively studied. However, more recently, there has been a growing interest in understanding the role of these experiences. This systematic review aims to address this research gap by systematizing the existing literature on PCEs and examining their rela...
Extracellular vesicles (EVs) (exossomes, microvesicles and apoptotic bodies) have been well acknowledged as mediators of intercellular communications in prokaryotes and eukaryotes. Lipids are essential molecular components of EVs but at the moment the knowledge about the lipid composition and the function of lipids in EVs is limited and as for now none lipidomic studies in Giardia EVs was described. Therefore, ...
The growing impact of automation and artificial intelligence (AI) on supply chain management and logistics is remarkable. This technological advance has the potential to significantly transform the handling and transport of goods. The implementation of these technologies has boosted efficiency, predictive capabilities and the simplification of operations. However, it has also raised critical questions about AI-...