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Analysis of Stereotyped B-Cell Receptor Frequencies Among Portuguese De Novo-Di...

Alves, Daniela; Ferreira, Gisela; Caldas, Joana; Fernandes, Mariana; Gaspar, Cátia; Alpoim, Mafalda; Carvalhais, Inês; Duarte, Sara; Silva, Helena

Background/objectives: Chronic lymphocytic leukemia (CLL) exhibits a heterogeneous clinical course influenced by genetic factors, such as the mutational status of immunoglobulin variable regions (IGHV). Recently, B-cell receptor (BcR) stereotypes have shown promising prognostic value, potentially surpassing IGHV status. The PAIS study analyzed BcR stereotypes and IGHV mutations in newly diagnosed Portuguese CLL...


Meta-analysis of Chemical exposure and increased risk of hematologic malignancies.

Ferreira, Gisela; Afreixo, Vera; Iutis, Adela; Silva, Raquel

Background: Exposure to environmental risk factors may be associated with the development of hematologic malignancies, as pointed by evidence in the literature. Despite this, most studies refer to a specific risk factor or disease. Objective: To assess this issue globally, in this study we performed a meta-analysis. Methods: A searched PubMed database was done in 2020 and a selection of 35 case-control and coho...


Benzene and other solvents exposure and incidence of hematologic malignancies

Iutis, Adela; Afreixo, Vera; Silva, Raquel M; Ferreira, Gisela



Thermoinhibition in parsley seeds

Silva, Tiago Alexandre da; Baldini, Luiz Felipe Guedes; Ferreira, Gisela; Nakagawa, João; da Silva, Edvaldo Aparecido Amaral

Temperature can exert great influence on germination, being considered optimal the temperature in which seed expresses its maximum germination potential in the shortest period of time. The germination of parsley seeds is slow, irregular and uneven. The aim of this study was to determine whether there is occurrence of thermodormancy or thermoinhibition of parsley seeds as a function of temperature variations. Th...

Date: 2017   |   Origin: Oasisbr

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Ferrari, Tainara Bortolucci; Ferreira, Gisela; Zucareli, Valdir; Boaro, Carmen Sílvia Fernandes

Effect of plant growth regulators on indices of growth analysis for sweet passion fruit seedlings (Passifl ora alata Curtis). The objective of this work was to investigate the effects of GA3 + IBA + cinetina on the growth of Passifl ora alata Curtis plants through growth analysis. The experiment was carried out by completely randomized block design, with six treatments and four replications. The plant growth re...

Date: 2011   |   Origin: Oasisbr

Allelopathic activity of fresh and dry extracts of Stryphnodendron adstringens ...

Manoel, Daniel Donini; Doiche, Caio Fernando Reis; Ferrari, Tainara Bortolucci; Ferreira, Gisela

The objective of this study aimed at the verification of the allelopatic action of extracts of “pata-devaca” (Bauhinia forficata Link) and “barbatimão” (Stryphnodendron adstringens (Mart.) Coville) on seeds of tomato (Lycopersicum esculentum Mill). Tomato seeds placed in translucent “gerbox” were treated with aqueous extracts prepared with fresh and dry leaves of the tested species at the following concentratio...

Date: 2009   |   Origin: Oasisbr

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Ferrari, Tainara Bortolucci; Ferreira, Gisela; Mischan, Martha Maria; Pinho, Sheila Zambello de

Sweet passion fruit (Passifl ora alata Curtis) germination: Phases and effect of plant growth regulator. This work aimed to characterize Passifl ora alata germination phases and evaluate the effects of GA3 and GA4+7, associated with phenylmethylaminepurine, on P. alata seed germination. Two experiments were conducted. In the fi rst, two treatments were carried out: seeds submerged in distilled water in a Becker...

Date: 2008   |   Origin: Oasisbr

Interaction between water and nutrient deficiencies in helianthus annuus

Fonseca, Filomena; David, Maria Manuela; Barrote, Isabel; Ferreira, Gisela; Correia, Maria João

The physiological response of plants to water deficits are known to vary according to the conditions of application of drought stress and the rate of development of leaf water deficits. At the whole plant level the effect of the water shess is usually perceived as a decrease in photosynthesis and growth, and is associated with alterations in C and N metabolism (McDonald and Davies, 1996). The decrease in water ...


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