165 documents found, page 1 of 17
A crossinggram for random fields on lattices
Ferreira, Helena; Ferreira, Marta Susana; Alexandre, Luís A.The modeling of risk situations that occur in a space framework can be done using max-stable random fields on lattices. Although the summary coefficients for the spatial behavior do not characterize the finite-dimensional distributions of the random field, they have the advantage of being immediate to interpret and easier to estimate. The coefficients that we propose give us information about the tendency of a ...
Olive yield and physicochemical properties of olives and oil in response to nut...
Silva, Ermelinda; Gonçalves, Alexandre; Martins, Sandra; Brito, Cátia; Ferreira, Helena; Ferreira, Luís M.M.; Moutinho-Pereira, José; Rodrigues, M.A.The effects of mineral fertilizers on the physicochemical properties of olives and oil under rainfed conditions is scarce. In this three-year study, the results of a nitrogen (N), phosphorus (P), potassium (K) and boron (B) fertilization trial carried out in a young rainfed olive grove and arranged as a nutrient omission trial are reported. The control consisted of the application of N, P, K and B (NPKB) and fo...
Moderate nitrogen rates applied to a rainfed olive grove seem to provide an int...
Silva, Ermelinda; Gonçalves, Alexandre; Martins, Sandra; Pinto, Luís; Rocha, Luís; Ferreira, Helena; Moutinho-Pereira, José; Rodrigues, M.A.Nitrogen (N) fertilization has been extensively studied all over the world, not only due to its impact on plant growth and yield, but also on product quality. Olive oil is a natural product highly valued by the markets, due to its role in the Mediterranean diet, but only when its quality is above legally established standards. Thus, it is important to continue to study how cropping practices can impact the qual...
Ascophyllum nodosum extract and glycine betaine preharvest application in grape...
Monteiro, Eliana; Baltazar, Miguel; Pereira, Sandra; Correia, Sofia; Ferreira, Helena; Alves, Fernando; Cortez, IsabelThe Douro Demarcated Region (DDR) has peculiar edaphoclimatic characteristics that provide a suitable terroir for premium wine production. As climate change effects continue to emerge, ensuring productivity and quality becomes increasingly important for viticulturists, as those directly determine their profits. Cultural approaches, such as the use of biostimulants, are actively being developed to mitigate abiot...
Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation
Gimondi, S.; Ferreira, Helena; Reis, R. L.; Neves, N. M.The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of diseases for which conventional therapies present serious limitations. Additionally, NPs can drastically improve early diagnosis and follow-up of many disorders. However, to harness their full capabilities, they must be precisely designed, produced, and tested in relevant models. Microfluidic systems can simulate dynamic flu...
On the size-dependent internalization of sub-hundred polymeric nanoparticles
Gimondi, Sara; Castro, Joana Isabel Martins Cosme Vieira; Reis, R. L.; Ferreira, Helena; Neves, N. M.The understanding of the interaction between nanoparticles (NPs) and cells is crucial to design nanocarriers with high therapeutic relevance. In this study, we exploited a microfluidics device to synthesize homogeneous suspensions of NPs with ≈ 30, 50, and 70 nm of size. Afterward, we investigated their level and mechanism of internalization when exposed to different types of cells (endothelial cells, macrophag...
Echinacea purpurea fractions represent promising plant-based anti-inflammatory ...
Vieira, Sara Filipa Fontoura; Gonçalves, Samuel M.; Gonçalves, Virgínia M. F.; Llaguno, Carmen P.; Macías, Felipe; Tiritan, Maria ElizabethEchinacea purpurea is traditionally used in the treatment of inflammatory diseases. Therefore, we investigated the anti-inflammatory capacity of E. purpurea dichloromethanolic (DE) and ethanolic extracts obtained from flowers and roots (R). To identify the class of compounds responsible for the strongest bioactivity, the extracts were fractionated into phenol/carboxylic acid (F1) and alkylamide fraction (F2)...
Overcoming challenges in pediatric formulation with a patient-centric design ap...
Ogbonna, John Dike N.; Cunha, Edite; Attama, Anthony A.; Ofokansi, Kenneth C.; Ferreira, Helena; Pinto, Susana; Gomes, Joana; Marx, ÍtalaDesigning oral formulations for children is very challenging, especially considering their peculiarities and preferences. The choice of excipients, dosing volume and palatability are key issues of pediatric oral liquid medicines. The purpose of the present study is to develop an oral pediatric solution of a model bitter drug (ranitidine) following a patient centric design process which includes the definition o...
Sex-Dependent Social and Repetitive Behavior and Neurochemical Profile in Mouse...
Ferreira, Helena; Sousa, Ana Catarina; Sereno, José; Martins, João; Castelo Branco, Miguel; Gonçalves, JoanaAutism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficits in social interaction, impaired communication, and repetitive behaviors. ASD presents a 3:1 ratio of diagnosed boys and girls, raising the question regarding sexual dimorphic mechanisms underlying ASD symptoms, and their molecular basis. Here, we performed in vivo proton magnetic resonance spectroscopy in juvenile male an...
A imagem projectante : impulso, travessia e rasto
Ferreira, HelenaStemming from my artistic practice, whose medium and recurring theme is the projection, this research consists of proposing and analysing the concept of the projecting image. In order to outline this concept, and distinguish it from the already known artistic category, the projected image (that combines both the notion of projection and screen), I seek to highlight the spatial, temporal and material dimensions,...