120 documents found, page 1 of 12
Position Statement of the Immunonephrology Working Group of the Portuguese Soci...
Nogueira, Estela; Oliveira, Nuno; Godinho, Iolanda; Lança, Alice; Inácio, António; Santos, Clara; Pinto, Helena; Laranjinha, Ivo; Vaz, RaquelSystemic lupus erythematosus (SLE) is a challenging immune ‑mediated disease that frequently involves the kidney as lupus nephritis (LN), an immune complex glomerulonephritis. Its occurrence is associated with increased morbidity and mortality and current treatment still fails to preserve renal function in the long term. As such, more efficacious and less toxic treatments are needed to treat LN, aiming to reduc...
The Role of Intercultural Communication in Fostering Organisational Creativity
Ferreira, Inês; Rua, Orlando LimaThis study aims to explore the impact of intercultural communication (IC) on organisational creativity (OC). Specifically, it analyses its contribution to organisational success, identifies challenges and advantages when integrating intercultural communication, and understands its effects on team creativity. A qualitative multiple-case study approach was adopted using purposive sampling involving semistructured...
A Descriptive Register of ANCA ‑ Positive Vasculitis Patients with Kidney Invo...
Santos, Adriana; Paulo, Núria; Marques, Nídia; Figueiredo, Rafael; Pinho, Ana; Pereira, Edite; Mariz, Eva; Neto, Ricardo; Ferreira, InêsIntroduction: Anti‑neutrophil cytoplasm antibody (ANCA)‑associated vasculitis (AAV) is a necrotizing disease affecting small blood vessels, commonly involving the kidneys, and associated with high morbidity and mortality.</p> Methods: We conducted a descriptive cross‑sectional study at Hospital de São João in Porto, including patients aged 18 or older with biopsy‑proven kidney involvement from AAV, fo...
Real-World Experience with Avacopan in ANCA-Associated Vasculitis in Portugal
Oliveira Correia, Sofia; Laranjinha, Ivo; Nogueira, Estela; Cunha, Anita; Tenazinha, Catarina; Pinto, Helena; Ferreira, Inês; Fernandes Serodio, JoãoIntroduction: Avacopan, a selective C5a receptor inhibitor, has emerged as a potential corticosteroid-sparing treatment in ANCA-associated vasculitis (AAV). This study aims to evaluate its real-world efficacy and safety in Portuguese patients with active AAV. Methods: We conducted a multicenter retrospective analysis of 15 adult patients with newly diagnosed or relapsing AAV treated with avacopan across nine ac...
The Critical Role of Multidisciplinary Teams inthe Management of Rare Systemic ...
Ferreira, Inês; Nogueira, Estela; Laranjinha, Ivo; Moura Jerónimo, Teresa; Godinho, Iolanda; Inácio, António; Oliveira Correia, Sofia; Lança, AliceRare systemic rheumatic diseases (RISD) with renal involvement, such as anti‑neutrophil cytoplasmic antibody (ANCA)‑associated vasculitis and systemic lupus erythematosus, require complex, coordinated care. These conditions often involve renal complications requiring specialized and timely intervention. Traditional care models, typically fragmented across specialties, are insufficient to meet the nuanced needs ...
Glucosylated cholesterol accumulates in atherosclerotic lesions and impacts mac...
Marques, André R.A.; Ferreira, Inês; Ribeiro, Quélia; Ferraz, Maria J.; Lopes, Elizeth; Pinto, Daniela; J. Hall, Michael; JS, Ramalho; Artola, MartaAtherosclerosis can be described as a local acquired lysosomal storage disorder (LSD), resulting from the build-up of undegraded material in lysosomes. Atherosclerotic foam cells accumulate cholesterol (Chol) and glycosphingolipids (GSLs) within lysosomes. This constitutes the ideal milieu for the formation of a side product of lysosomal storage: glucosylated cholesterol (GlcChol), previously found in several L...
Storage, moving and re-storage of Municipal Oporto collections
Aguiar, Maria; Ferreira, Inês; Teixeira, Mariana; Barata, Carolina; Cabral, AnaWithin a wider collections management programme conducted by the Divisão Municipal de Museus (DMM) from Oporto City Hall, a collaboration has been started with the Portuguese Catholic University (UCP) for reorganisation of the municipal storage facilities and to set up the process of transfering collections to permanent housing in a refurbished building. The main goals of the project are to prepare the collecti...
Nasal obstruction in the newborn: An unusual cause
Alves Araújo, Sara; Soares Santos, Tiago; Miranda, Vera; Ferreira, InêsNasal obstruction is clinically relevant in neonates because they are obligate nasal breathers. Several causes should be considered, namely congenital anomalies of the nasal cavity leading to obstruction/stenosis. Although rare, choanal atresia/stenosis should always be considered upfront in the differential diagnosis. The authors report the case of a newborn with severe nasal obstruction and signs of respirato...
(NON-)COMPLIANCE WITH THE LAW OF ADMINISTRATIVE MODERNIZATION. CONSIDERATIONS A...
Ferreira, InêsPortuguese legislation has provided for the protection of issues related to the state's communication with citizens since 1966 (Article 6 of the Civil Code) and 1989 (Article 20 of the Constitution of the Portuguese Republic). In 1999, Article 16 of the Administrative Modernisation Law provided more specific support for this issue (as did Article 2(g), added in 2014). Although previous provisions had already de...
A integração dos ODS em unidades curriculares do Departamento de Direito da UPT...
Alves, Dora Resende; Ferreira, InêsLançado o desafio de apresentar de modo muito concreto a integração dos Objetivos do Desenvolvimento Sustentável (ODS) nas unidades curriculares do Departamento de Direito da UPT, remete-se para o comportamento docente e discente no 1.º ciclo de estudos em Direito no Departamento em causa, em conjunto com uma estudante. [...]