Background: Mentha piperita L., widely recognized as peppermint, is globally renowned and popular due to its versatile applications in medicine, industry, and cuisine [1]. This perennial plant has a worldwide distribution, with origins in Europe and Middle East. As member of the Lamiaceae family it’s a natural hybrid of Mentha aquatic L. and Mentha spicata L. [1]. Traditionally, it has been used for alleviating...
The increasing prevalence of neurodegenerative diseases such as Alzheimer's disease (AD) underscores the need for effective therapeutic strategies. Nanotechnology can provide new tools to counteract neurotoxicity, namely by improving bioavailability of therapeutic molecules in the brain. Brown seaweeds, such as Fucus spiralis (FS), are rich in bioactive compounds with antioxidant, anti-inflammatory, cytoprotect...
Fouling is a major challenge for marine aquaculture infrastructures, and copper-based antifouling products are commonly used to address this issue. The wider adoption of multitrophic aquaculture to sustainably produce multiple species is encouraged worldwide, as it promotes nutrient recycling while reducing problems associated with contaminants. In this study, Mytilus sp. and Laminaria ochroleuca were exposed, ...
Systemic lupus erythematosus (SLE) is a challenging immune ‑mediated disease that frequently involves the kidney as lupus nephritis (LN), an immune complex glomerulonephritis. Its occurrence is associated with increased morbidity and mortality and current treatment still fails to preserve renal function in the long term. As such, more efficacious and less toxic treatments are needed to treat LN, aiming to reduc...
This study aims to explore the impact of intercultural communication (IC) on organisational creativity (OC). Specifically, it analyses its contribution to organisational success, identifies challenges and advantages when integrating intercultural communication, and understands its effects on team creativity. A qualitative multiple-case study approach was adopted using purposive sampling involving semistructured...
Introduction: Anti‑neutrophil cytoplasm antibody (ANCA)‑associated vasculitis (AAV) is a necrotizing disease affecting small blood vessels, commonly involving the kidneys, and associated with high morbidity and mortality.</p> Methods: We conducted a descriptive cross‑sectional study at Hospital de São João in Porto, including patients aged 18 or older with biopsy‑proven kidney involvement from AAV, fo...
Introduction: Avacopan, a selective C5a receptor inhibitor, has emerged as a potential corticosteroid-sparing treatment in ANCA-associated vasculitis (AAV). This study aims to evaluate its real-world efficacy and safety in Portuguese patients with active AAV. Methods: We conducted a multicenter retrospective analysis of 15 adult patients with newly diagnosed or relapsing AAV treated with avacopan across nine ac...
Rare systemic rheumatic diseases (RISD) with renal involvement, such as anti‑neutrophil cytoplasmic antibody (ANCA)‑associated vasculitis and systemic lupus erythematosus, require complex, coordinated care. These conditions often involve renal complications requiring specialized and timely intervention. Traditional care models, typically fragmented across specialties, are insufficient to meet the nuanced needs ...
Within a wider collections management programme conducted by the Divisão Municipal de Museus (DMM) from Oporto City Hall, a collaboration has been started with the Portuguese Catholic University (UCP) for reorganisation of the municipal storage facilities and to set up the process of transfering collections to permanent housing in a refurbished building. The main goals of the project are to prepare the collecti...
Introduction: Environmental pollutants such as tetrabromobisphenol A (TBBPA), perfluoroalkyl substances (PFASs) like perfluorooctanoic acid (PFOA), and endocrine-disrupting compounds (EDCs) as 17α-ethinylestradiol (EE2) are commonly detected in coastal ecosystems. The Mediterranean mussel, Mytilus galloprovincialis, is a species of significant ecological and economic importance. Recent genomic studies have reve...