2 documents found, page 1 of 1
Investigating true β-lactam allergy in the outpatient allergy clinics at a publ...
Francelino, Eudiana Vale; Araújo, Sarah Resende; Ferreira, Janaira Fernandes Severo; Araújo, Fabiane Milena de CastroObjective: The aim of the study was to investigate true β-lactam allergy at a public pediatric hospital. Material and Methods: Children and adolescents with allergy symptoms were referred to the Allergy and Immu-nology Service, Hospital Infantil Albert Sabin, Fortaleza, Brazil. During the allergist interviews, β-lactam drug allergy was suspected in 24 patients. Results: Urticaria, angioedema, erythematous macul...
Polymorphism of IL10, IL4, CTLA4, and DAO genes in cross-reactive nonsteroidal ...
Vasconcelos, Luciana Mabel Ferreira; Rodrigues, Raphael de Oliveira; Albuquerque, Andressa Almeida; Barroso, Gabrielle Dantheias; Sasahara, Greyce LuriOur aim was to evaluate genetic polymorphism of molecules involved in immunoregulatory/allergic processes in patients who presented with cutaneous hypersensitivity caused by chemically unrelated nonsteroidal anti-inflammatory drugs. Polymorphisms at IL10 (–1082 G>A), IL4 (–589 C>T), CTLA4 (+49A>G), and DAO (+8956 C>G) genes were studied in 55 cases and 97 controls by the polymerase chain reaction-restriction fr...