126 documents found, page 1 of 13
A Portuguese expert panel position paper on the management of heart failure wit...
Silva-Cardoso, José; Moreira, Emília; Melo, Rachel Tavares de; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, BrendaIn Portugal, a 15.2% prevalence of heart failure with preserved ejection fraction (HFpEF) was recently identified among those aged ≥50 years. HFpEF represents 90% of Portuguese heart failure patients. HFpEF management in Portugal is challenging due to patient heterogeneity, diagnostic and therapeutic complexity, and organizational constraints on the healthcare system. Considering the above, a panel of Portugues...
A Portuguese expert panel position paper on the management of heart failure wit...
Silva-Cardoso, José; Moreira, Emília; Melo, Rachel Tavares de; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, BrendaHeart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as we...
A Portuguese Expert Panel Position Paper on the Management of Heart Failure wit...
Silva-Cardoso, José; Moreira, Emília; Tavares de Melo, Rachel; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, BrendaIn Portugal, a 15.2% prevalence of heart failure with preserved ejection fraction (HFpEF) was recently identified among those aged ≥50 years. HFpEF represents 90% of Portuguese heart failure patients. HFpEF management in Portugal is challenging due to patient heterogeneity, diagnostic and therapeutic complexity, and organizational constraints on the healthcare system. Considering the above, a panel of Portugues...
Relatório de Estágio Curricular – Associação Portuguesa de Pais e Amigos do Cid...
Ferreira, JorgeEste documento é o Relatório do Estágio realizado no âmbito do 3º Ano, do Curso de Licenciatura em Animação Sociocultural, da Escola Superior de Educação, Comunicação e Desporto do Instituto Politécnico da Guarda. O estágio foi desenvolvido no Estabelecimento Dr. Víctor Fontes, pertencente à Associação Portuguesa de Pais e Amigos do Cidadão Deficiente Mental de Viseu, no período entre 26 de fevereiro e 1 de jul...
Geometry optimisation of a wave energy converter
Costa, Susana; Ferreira, Jorge; Martins, NelsonThe geometry optimisation of a point-absorber wave energy converter, focusing on the increase in energy absorption derived from heave forces, was performed. The proposed procedure starts by developing an initial geometry, which is later evaluated in terms of hydrodynamics and optimised through an optimisation algorithm to tune the shape parameters that influence energy absorption, intending to obtain the optima...
TROPPO: tissue-specific reconstruction and phenotype prediction using omics data
Oliveira, Alexandre Rafael Machado; Ferreira, Jorge; Vieira, Vítor; Sá, Bruno; Rocha, MiguelThe increasing availability of high-throughput technologies in systems biology has advanced predictive tools like genome-scale metabolic models. Despite this progress, integrating omics data to create accurate, context-specific metabolic models for different tissues or cells remains challenging. A significant issue is that many existing tools rely on proprietary software, which limits accessibility. We introduc...
Determination of parental origin of Gestational Trophoblastic Disease using MS-...
Cardoso , Sara; Ferreira, Jorge; Silva Santos , Rui; Lopes , Paula; Pinto , Carla; Rodrigues, Marta; Pinho, Maria João; Capela, Liliana; Dória, SofiaBackground: Gestational trophoblastic disease (GTD) is a rare condition marked by abnormal proliferation of placental trophoblastic cells and encompasses a heterogeneous group of disorders with distinct clinical, imaging, and histological features, each requiring tailored therapeutic approaches. Although GTD generally has a good prognosis, early diagnosis, targeted treatment, and continuous surveillance are ess...
A Portuguese expert panel position paper on the management of heart failure wit...
Silva-Cardoso, José; Moreira, Emília; Tavares de Melo, Rachel; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mario; Gavina, Cristina; Moura, BrendaHeart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as we...
Modelling therapeutic response in asthmatic adults: a previous exploratory anal...
Alves, Cristina; Faria, Brígida Mónica; Alves, Sandra Maria; Ferreira, Jorge; Faria, Brigida Monica; Alves, Sandra MariaAsthma is a respiratory disease characterized by chronic inflammation of the airways. Effective asthma management is essentially based on choosing the appropriate treatment for each individual (1). Data science and machine learning models offer valuable insights and enhance the outcomes achieved in asthma management (2). The main objective is to develop predictive models for therapy response in patients with as...
Multidisciplinary cardiorenal program for heart failure patients: Improving out...
Calça, Rita; Malho, Anabela; Domingos, Ana Teresa; Fernandes, Raquel Menezes; Silva, Francisca Gomes da; Aguiar, Carlos; Tralhão, AntónioThe cardiorenal program (CRP), implemented within a specialized heart failure and kidney disease clinic, encompasses a multidisciplinary approach to the management of patients with heart failure and kidney disease. It focuses on optimizing therapy and improving patient outcomes. The CRP includes a range of services, including clinical evaluation, diagnostic testing, medical treatment, and patient education. The...