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Bridging Complexity: Business Incubators in the Preliminary Lens of System Dyna...

Almeida, Diogo Costa; Afonso, Paulo; Soares, Ana Maria; Ferreira, L. P.

System dynamics simulation has been a field of study with applications in various areas and whose main objective is to study complex and dynamic systems and, more specifically, to determine the impact that certain configurations of controllable inputs have on the various output measures of these systems. Business incubators are organizations with the aim of promoting entrepreneurship and the success of the star...


Reconfiguration of assembly lines using lean thinking in an electronics compone...

Bastos, N. M.; Alves, Anabela Carvalho; Castro, F. X.; Duarte, J.; Ferreira, L. P.; Silva, F. J. G.

This article discusses the reconfiguration and improvement of electronics components assembly lines through the use of Lean Thinking principles. This reconfiguration was undertaken in a project that followed the action-research methodology. There were three main distinct problems related with the outdated assembly lines. The first came from a diagnosis of the assembly line itself, where quality problems and dif...


A novel automated system for the handling of car seat wires on plastic over-inj...

Silva, F. J. G.; Soares, M. R.; Ferreira, L. P.; Alves, Anabela Carvalho; Brito, M.; Campilho, R. D. S. G.; Sousa, V. F. C.

The structure of car seats is becoming increasingly complex, with mixing of wire conformation and plastic injection. The plastic over-molding process implies some labor, which can be reduced if novel solutions are applied in this manufacturing area. The handling of the wires used in car seats is the main problem identified in the process, wasting time both in the feeding and in the extraction of the molds used ...


Chapter 25. Decellularized Matrix Hydrogels for In Vitro Disease Modeling

Ferreira, L. P.; Monteiro, M. V.; Gaspar, V. M.; Mano, J. F.

The extracellular matrix (ECM) operates as a complex network of cell-supporting macromolecules in tissue homeostasis and disease scenarios. Given ECM structural and bio-signaling roles, understanding and modeling matrix components and their dysfunction in disease is crucial for the development of novel therapeutic approaches for numerous pathologies including pulmonary, renal and intestinal fibrosis, osteoarthr...


Using lean thinking principles to reduce wastes in reconfiguration of car radio...

Oliveira, M. S.; Moreira, H. D.A.; Alves, Anabela Carvalho; Ferreira, L. P.

Assembly lines are production systems designed to be oriented to the product and well known to be highly productive. Nevertheless, during this time-frame the product volumes could decrease and the assembly lines, previously very productive and efficient, becomes unproductive and inefficient. This happens in the car electronics components company where this study took place that due to customer's demand decrease...


Bioinstructive microparticles for self-assembly of mesenchymal stem Cell-3D tum...

Ferreira, L. P.; Gaspar, V. M.; Mano, J. F.

3D multicellular tumor spheroids (3D-MCTS) that closely mimic in vitro the complex lung tumor microenvironment (TME) are highly desirable for screening innovative anti-cancer therapeutics. Despite significant improvements in mimicking lung TME, few models have combined tumor-infiltrating mesenchymal stem cells from bone marrow (hBM-MSCs) with heterotypic 3D tumor spheroid models containing ECM mimetic component...


Magnesium doping on brownmillerite Ca2FeAlO5

Malveiro, J.; Ramos, T.; Ferreira, L. P.; Waerenborgh, J. C.; Nunes, M. R.; Godinho, M.; Carvalho, M. D.

Ca2FeAl1-xMgxO5 (x=0, 0.05 and 0.1) compounds adopting the brownmillerite-type structure were prepared by a self-combustion route using two different fuels. Characterisation was performed using X-ray powder diffraction, Mössbauer spectroscopy, magnetisation measurements, chemical analysis, scanning electron microscopy and 4-point dc conductivity measurements. Global results indicate that the solubility limit wa...


Structural and Magnetic Characterization of the Series La1-xSrxFe0.8Cr0.2O3-δ (...

Ramos, T.; Carvalho, M. D.; Ferreira, L. P.; Cruz, M. M.; Godinho, M.

A series of perovskite compounds with the general formula La1-xSrxFe0.8Cr0.2O3-δ (x = 0.2, 0.4, 0.6, and 0.8) have been synthesized using a urea/nitrates self-combustion route. Their characterization was performed using room-temperature X-ray diffraction, electrical and magnetization measurements. A structural transition from orthorhombic (x = 0.2) to rhombohedral (x > 0.2) was determined. Among the rhombohedra...


Study of RFe12−xMox (R =Y, Ho) compounds by neutron powder diffraction, ac susc...

Campos, J. Ayres de; Ferreira, L. P.; Cruz, M. M.; Gil, J. M.; Mendes, P. J.; Ferreira, I. C.; Bacmann, M.; Soubeyroux, J.-L.; Fruchart, D.; Godinho, M.

Neutron powder diffraction, magnetization and ac susceptibility measurements were performed on compounds of the series RFe12−xMox (R D Y and Ho, x D 1, 2, 3). The influence of the Mo content on both structural and magnetic properties is discussed. Comparison with published data for different Mo concentrations is made. It is found that the effect of Mo substitution for Fe on structural and magnetic properties ca...


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