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cipC is important for Aspergillus fumigatus virulence

Ferreira, Márcia Eliana da Silva

Date: 2017   |   Origin: Oasisbr


Comparative genomic analysis of human fungal pathogens causing paracoccidioidom...

Desjardins, Christopher A.; Champion, Mia D.; Holder, Jason W.; Muszewska, Anna; Goldberg, Jonathan; Bailão, Alexandre Melo; Brígido, Marcelo de Macedo

Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, is coupled with a thermally regulated transition from a soil-dwelling filamentous form to a yeast-like pathogenic form. To better understand the genetic basis of growth and pathogenicity in ...

Date: 2013   |   Origin: Oasisbr

The conserved and divergent roles of carbonic anhydrases in the filamentous fun...

Han, Kap-Hoon; Chun, Yoon-Hee; Figueiredo, Bárbara de Castro Pimentel; Soriani, Frederico Marianetti; Savoldi, Marcela; Almeida, Agostinho João Ramalho

Carbon dioxide (CO(2)) and its hydration product bicarbonate (HCO(3)(-)) are essential molecules in various physiological processes of all living organisms. The reversible interconversion between CO(2) and HCO(3)(-) is in equilibrium. This reaction is slow without catalyst, but can be rapidly facilitated by Zn(2+)-metalloenzymes named carbonic anhydrases (CAs). To gain an insight into the function of multiple c...


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