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Anti-corrosion and cytotoxicity properties of inorganic surface treatments on M...

Neves, CS; Sousa, I; Freitas, MA; Moreira, L; Costa, C; Teixeira, JP; Fraga, S; Silva, RM; Silva, RF; Starykevich, M; Scharnagl, N; Zheludkevich, ML

In this work biodegradable Mg1Ca alloy underwent surface modification using hydroxyapatite (HAp), aluminium oxide (Al2O3), and treatments with phosphoric (H3PO4), hydrofluoric (HF), and acetic (CH3COOH) acids. The resulting surface-treated Mg substrates were assessed in terms of phase content and chemical composition through X-ray diffraction (XRD) and glow discharge optical emission spectrometry (GDOES). Addit...


Insights into corrosion behaviour of uncoated Mg alloys for biomedical applicat...

Neves, CS; Sousa, I; Freitas, MA; Moreira, L; Costa, C; Teixeira, JP; Fraga, S; Pinto, E; Almeida, A; Scharnagl, N; Zheludkevich, ML; Ferreira, MGS

MgCa and MgGd series of alloys are often reported as promising candidates for biomedical applications. In the present study, cytotoxicity and corrosion behavior of Mg1Ca and Mg10Gd alloys in different electrolytes (NaCl, PBS, MEM) have been investigated in order to make a direct comparison and understand the mechanisms behind their performance. Potentiodynamic polarization and electrochemical impedance spectros...


Gold nanorods induce early embryonic developmental delay and lethality in zebra...

Mesquita, B; Lopes, I; Silva, S; Bessa, MJ; Starykevich, M; Carneiro, J; Galvão, LP; Ferreira, MGS; Tedim, J; Teixeira, JP; Fraga, S

Due to their unique electronic and optical features, gold nanoparticles (AuNP) have received a great deal of attention for application in different fields such as catalysis, electronics, and biomedicine. The large-volume manufacturing predicted for future decades and the inevitable release of these substances into the environment necessitated an assessment of potential adverse human and ecological risks due to ...


Biocompatibily of acrylic bone cement

Bettencourt, A; Calado, A; Alfaia, AJI; Montemor, MF; Ferreira, MGS; Vale, FM; Monteiro, J; Castro, M


Surface studies on acrylic bone cement

Bettencourt, A; Calado, A; Amaral, J; Alfaia, A; Vale, FM; Monteiro, J; Montemor, MF; Ferreira, MGS; Castro, M

Poly(methyl methacrylate) (PMMA) is used to fill the gap between the prosthesis and the surrounding bone in cemented arthroplasties. Biocompatibility problems related to bone cement application limit the clinical success of these cemented arthroplasties. Being the cement surface in close connection with the living bone, it is reasonable to assume that surface properties such as, surface composition and surface ...


The effect of ethanol on acrylic bone cement

Bettencourt, A; Calado, A; Amaral, J; Vale, FM; Rico, JMT; Monteiro, J; Montemor, MF; Ferreira, MGS; Castro, M

Prosthesis loosening is a major problem associated with the use of poly(methyl methacrylate) (PMMA) bone cement that may be related to a peri-implant vacuolisation commonly observed at bone-cement interface. Methyl methacrylate (MMA) monomer may be one of the cement components partly responsible for the mentioned vacuolisation due to a cytotoxic effect associated to this compound. Alcoholism has been related to...


The effect of ethanol on bone cement biocompatibility

Bettencourt, A; Calado, A; Amaral, J; Vale, FM; Monteiro, J; Montemor, MF; Ferreira, MGS; Castro, M


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