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Delayed Presentation of Isolated Grade III Pancreatic Injury - a Case Report

Ferreira, MJ; Gallardo, G; Vigia, E; Filipe, E; Pinto Marques, H

Because of their vague and subtle indications and symptoms, pancreatic injuries are frequently misdiagnosed. It's crucial to have a high level of clinical suspicion. The presence of other organ solid lesions and vascular injuries, as well as the patient's hemodynamic condition, will determine how these injuries are treated. A surgical approach is mandatory when a ductal disruption occurs. The case of a 32-year-...


Oral glucose tolerance testing at 1 h and 2 h: relationship with glucose and ca...

Guerreiro, V; Maia, I; Neves, JS; Salazar, D; Ferreira, MJ; Mendonça, F; Silva, MM; Borges-Canha, M; Viana, S; Costa, C; Pedro, J; Varela, A; Lau, E

Background: One hour plasma glucose concentration (1hPG) during an oral glucose tolerance test (OGTT) may be an alternative to 2-h plasma glucose concentration (2hPG) in the identification of individuals at increased risk of hyperglycaemia, although its role is not fully understood. Aim: We aim to investigate the relationship of these measures with other glucose parameters, as well as their relationship with ca...


Prognostic Value of Isolated Elevated Troponin I Levels in Patients without Acu...

Domingues, C; Ferreira, MJ; Ferreira, JM; Marinho, AV; Alves, PM; Ferreira, C; Fonseca, I; Gonçalves, L

Background: Although non-ischemic troponin elevation is frequently seen in patients admitted to the emergency department (ED), consensus regarding its management is lacking. Objectives: This study aimed to characterize patients admitted to the ED with non-ischemic troponin elevation and to identify potential mortality predictors in this population. Methods: This retrospective observational study included ED pat...


The impact of vitamin d in non-alcoholic fatty liver disease: A cross-sectional...

Borges-Canha, M; Neves, JS; Mendonça, F; Silva, MM; Costa, C; Cabral, PM; Guerreiro, V; Lourenço, R; Meira, P; Salazar, D; Ferreira, MJ; Pedro, J

Purpose: We aimed to evaluate the association between vitamin D status and hepatic function parameters and scores: Fatty Liver Index (FLI, predictor of hepatic steatosis) and BARD (BMI, AST/ALT ratio and DM, predictor of hepatic fibrosis) in patients with morbid obesity. Patients and Methods: Cross-sectional study including patients with morbid obesity followed in our centre between January 2010 and July 2018. ...


Beta Cell Function as a Baseline Predictor of Weight Loss After Bariatric Surgery

Borges-Canha, M; Neves, JS; Mendonça, F; Silva, MM; Costa, C; M Cabral, P; Guerreiro, V; Lourenço, R; Meira, P; Salazar, D; Ferreira, MJ; Pedro, J

Background: Obesity is a multifactorial disease, which is strongly associated to other metabolic disorders. Bariatric surgery is the most effective treatment of morbid obesity. The role of beta cell function in weight loss after bariatric surgery is uncertain. Aim: To evaluate the association between beta cell function and percentage of total body weight loss (TBWL%) 1, 2, 3, and 4 years after bariatric surgery...


Avascular femoral necrosis as part of Cushing syndrome presentation: a case report

Salazar, D; Esteves, C; Ferreira, MJ; Pedro, J; Pimenta, T; Portugal, R; Carvalho, D

Background: The clinical characteristics and complications of Cushing syndrome (CS) are well known and described in the literature. Nevertheless, rare, atypical presentations may go unnoticed. Osteonecrosis is a well-documented complication of glucocorticoid therapy. However, endogenous hypercortisolism is a rare, but relevant, cause of bone avascular necrosis. We describe the case of a woman with CS undiagnose...


Correction to: Avascular femoral necrosis as part of Cushing syndrome presentat...

Salazar, D; Esteves, C; Ferreira, MJ; Pedro, J; Pimenta, T; Portugal, R; Carvalho, D


Adequate magnesium level as an associated factor of pre-diabetes and diabetes m...

Guerreiro, V; Maia, I; Neves, JS; Salazar, D; Ferreira, MJ; Mendonça, F; Silva, MM; Viana, S; Costa, C; Pedro, J; Varela, A; Lau, E; Freitas, P

Bariatric surgery (BS) can lead to remission of type 2 diabetes mellitus (T2DM), however, the evidence on the influence of preoperative serum magnesium levels on this reversal is scarce. To study the influence of preoperative serum magnesium levels on the pre-T2DM and T2DM remission one year after BS. Retrospective study carried out among 1656 patients with obesity who underwent BS in the Centro Hospitalar Univ...


Cushing's syndrome: Consequences of late diagnosis after bariatric surgery

Pedro, J; Belo, S; Guerreiro, V; Ferreira, MJ; Salazar, D; Costa, C; Esteves, C; Pereira, J; Freitas, P; Carvalho, D

Prior to bariatric surgery, endocrine causes of obesity must be excluded. The diagnosis of osteoporosis in a male requires the study of secondary causes of this condition. The diagnostic delay of Cushing's syndrome may have irreversible consequences.


ARMC5 Primary Bilateral Macronodular Adrenal Hyperplasia Associated with a Meni...

Ferreira, MJ; Pedro, J; Salazar, D; Costa, C; Aragão Rodrigues, J; Costa, MM; Grangeia, A; Castedo, JL; Carvalho, D

Primary bilateral adrenal macronodular hyperplasia is characterized by functioning adrenal macronodules and variable cortisol secretion. Familial clustering suggests a genetic cause that has been confirmed with the identification of some genetic mutations, including inactivating germline mutations, in armadillo repeat containing 5 (ARMC5) gene. The identification of the pathogenic variant enables the physician ...


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