Auxemma oncocalyx Taub. belongs to the Boraginaceae family and is native from the northeastem caatings where is know as “pau branco”. The stem bark of the tree is adstringent and popularly used in the treatment of wounds. The objective of the present work was to study toxicological effects and pharmacological activities of the hydrosoluble fraction isolated from the heartwood of A. oncocalyx. This fraction pres...
INTRODUÇÃO: No ano de 2011 foram registrados no Centro de Assistência Toxicológica do Instituto Dr. José Frota (CEATOX-IJF) 3225 casos de exposição humana a agentes tóxicos. Destes, 454 envolveram crianças entre 0 a 12 anos de idade. Dentre os toxicantes, os medicamentos foram os principais responsáveis por esses eventos tóxicos, sendo o haloperidol o medicamento envolvido com maior frequência. Intoxicações por...
INTRODUÇÃO: Os medicamentos têm papel fundamental no tratamento e controle de diversas enfermidades, porém não são isentos de riscos, podendo causar efeitos deletérios quando usados de forma inadequada. No Brasil, entre outros grupos de agentes químicos, os medicamentos vêm se destacando como os principais agentes responsáveis por casos de intoxicação humana e apresentando altas taxas de mortalidade. Inúmeras r...
Local anesthetics are commonly used in surgical procedures, they are able to promote a reversible blockade of nerve conduction, with loss of sensation in circumscribed area of the body without changing the individual's level of consciousness. The aim of this study was to review the literature that can compose the body of evidence on efficacy and safety of Lipid Emulsion (ELI) for use as an antidote in the treat...
To verify the health status in the elderly who have suffered accidents and treated at a reference hosp ital for emergency care of Ceará, Brazil. This is a cross-se ctional, descriptive study, with quantitative appro ach, developed in an emergency hospital in the city of Fortaleza. For the sample, 182 elderly people were selected. T he data were collected using the BOAS Questionnaire as a tool, e xported to the ...
The local anesthetic technique when performed with a quality product results in the abolition of autonom ic and sensory motors functions . The c ardiotoxicity caused by local anesthetics is a hard condition to manage, given traditional therapies, which are quite limited. Thus, it is crucial to evaluate the clinical fea sibility of using Lipid Emulsion (LE) intravenously in the treatment of poisoning by local an...
Local anesthetics (LAs) are essential for most invasive procedures. This study aimed to evaluate the various systemic problems due to the indistinct use of LAs. Were used following sources: electronic databases such as PUBMED, MEDLINE, LILACS and BBO, articles in books and periodicals published between the years 2005 to 2012. The descriptors were used: local anesthetics, toxicity, adverse effects and systemic c...