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Underuse of reperfusion therapy with systemic thrombolysis in high-risk acute p...

Martinho, Mariana; Calé, Rita; Grade Santos, João; Rita Pereira, Ana; Alegria, Sofia; Ferreira, Filipa; José Loureiro, Maria; Judas, Tiago

Introduction: Reperfusion therapy is generally recommended in acute high-risk pulmonary embolism (HR-PE), but several population-based studies report that it is underused. Data on epidemiology, management and outcomes of HR-PE in Portugal are scarce. Objective: To determine the reperfusion rate in HR-PE patients, the reasons for non-reperfusion, and how it influences outcomes. Methods: In this retrospective coh...


Chronic Histiocytic Intervillositis: A Rare Cause of Placenta Mediated Obstetri...

Ferreira, Melanie; Fonseca, Ana Glória; Cunha, Vitória; Almeida, Maria Manuela; Santos, Antónia; Ilgenfritz, Raquel

The authors report a case of a 31-year-old woman, pregnantfor the third time, with a medical history of severe placentalmediated obstetrical complications, referred for exclusion ofa pro-thrombotic state. Thrombophilia testing was negative,however isolated alkaline phosphates elevation (10 times superiorto the upper reference limit) was detected. Alkalinephosphatase elevation that does not surpass twice the upp...


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