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Intensive monitoring studies for assessing medicines : a systematic review

Torre, Carla; Cary, Maria; Borges, Fábio Cardoso; Ferreira, Paula S.; Alarcão, Joana; Leufkens, Hubert G.; Costa, João; Martins, Ana Paula

Introduction: Intensive monitoring (IM) is one of the methods of post-marketing active surveillance based upon event monitoring, which has received interest in the current medicines regulatory landscape. For a specific period of time, IM involves primary data collection and is actively focused on gathering longitudinal information, mainly safety, since the first day of drug use. Objectives: To describe IM syste...


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