Made available in DSpace on 2019-10-06T16:44:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-22; Background: Chronic hepatic diseases are serious problems worldwide, which may lead to the development of fibrosis and eventually cirrhosis. Despite the significant number of people affected by hepatic fibrosis, no effective treatment is available. In the liver, hepatic stellate cells are the major fibr...
Made available in DSpace on 2018-12-11T16:52:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The development of new therapeutic strategies to control or reverse hepatic fibrosis requires thorough knowledge about its molecular and cellular basis. It is known that the heptapeptide angiotensin-(1–7) [ang-(1–7)] can reduce hepatic fibro...