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Assessment of calcinosis in Portuguese patients with systemic sclerosis: a mult...

Samões, Beatriz; Guimarães da Fonseca, Diogo; Beirão, Tiago; Costa, Flávio; Vieira, Romana; Terroso, Georgina; Ferreira, Raquel Miriam; Nicolau, Rafaela

Introduction/objectives: The study aims to define the clinical and subclinical calcinosis prevalence, the sensitivity of radiographed site and clinical method for its diagnosis, and the phenotype of Portuguese systemic sclerosis (SSc) patients with calcinosis. Method: A cross-sectional multicenter study was conducted with SSc patients fulfilling Leroy/Medsger 2001 or ACR/EULAR 2013 classification criteria, regi...


Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, Jose; Sepriano, Alexandre; Rodrigues-Manica, Santiago; Pimentel-Santos, Fernando; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime Cunha

Objectives To compare definitions of high disease activity of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in selecting patients for treatment with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods Patients from Rheumatic Diseases Portuguese Register ( R euma. pt) with a clinical diagnosis of axial spondyloarthritis (ax...


Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, Jose; Sepriano, Alexandre; Rodrigues-Manica, Santiago; Pimentel-Santos, Fernando; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime Cunha

Objectives: To compare definitions of high disease activity of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in selecting patients for treatment with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods: Patients from Rheumatic Diseases Portuguese Register (Reuma.pt) with a clinical diagnosis of axial spondyloarthritis (axS...


Effectiveness of switching between TNF inhibitors in patients with axial spondy...

Manica, Santiago Rodrigues; Sepriano, Alexandre; Pimentel-Santos, Fernando; Gouveia, Nélia; Barcelos, Anabela; Branco, Jaime C.; Bernardes, Miguel

Background: To investigate whether the reason to discontinue the first TNF inhibitor (TNFi) affects the response to the second TNFi in axial spondyloarthritis (axSpA). Methods: Patients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started the second TNFi between June 2008 and May 2018, were included. Response was assessed by the Ankylosing Spondylit...


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