72 documents found, page 1 of 8

Chronic thromboembolic pulmonary hypertension: a comprehensive review of pathog...

Chronic thromboembolic pulmonary hypertension (CTEPH) is part of group 4 of the pulmonary hypertension (PH) classification and generally affects more than a third of patients referred to PH centers. It is a three-compartment disease involving proximal (lobar-to-segmental) and distal (subsegmental) pulmonary arteries that are obstructed by persistent fibrothrombotic material, and precapillary pulmonary arteries ...

Predicting the burden for surgical aortic valve replacement in a tertiary centr...

Background/Objectives: The incidence of aortic stenosis (AS) is predicted to rise with the aging population, emerging as a growing public health challenge in developed countries, leading to an increased demand for intervention. Our aim is to predict the evolution of proposed cases for SAVR in the geographic referral area of our tertiary hospital until 2041. Methods: We used data from the Portuguese Census for 2...

Otimização de formulações de extrusão de zeólitos recorrendo a planeamento fato...

Um planeamento de experiencias fatorial completo foi utilizado, abrangendo três variáveis independentes em dois níveis, para avaliar os principais parâmetros que influenciam o processo de extrusão. O estudo teve como objetivo otimizar as propriedades do extraído em relação ‡ microporosa ade e ‡ resistência mecânica. As variáveis investigadas incluíram o teor de zeólito (% mássica), a razão ácido/aglomerante (m/...

A reviewed approach to vitamin D supplementation in pediatric age in Portugal

Vitamin D deficiency is a well-established cause of rickets in children and has been reported as associated to impacts on other systems and organs. Vitamin D deficiency and insufficiency are pediatric worldwide global health problems. Although data on the prevalence of vitamin D deficiency and insufficiency in the Portuguese pediatric population are scarce, data for Portuguese subpopulations and equivalent regi...

Microbiological profile of vegan and vegetarian meat analogues from the Portugu...

Motivation: Meat analogues, especially those of plant origin, are generally high in protein, high in water activity (aw > 0.95) and have a mildly acidic pH (pH > 5.5) (Kabisch et al., 2024), making these products highly susceptible to microbial spoilage. With the current increase in consumption of meat analogues, their food safety aspects need to be considered and the question arises: can meat analogs pose a fo...

Hyperthermic Intrathoracic Chemotherapy. A new weapon has been deployed in Port...

Thymoma is a relatively rare tumour, being, nonetheless, the most frequent neoplasm of the anterior mediastinum. Radical surgery is the gold-standard in every stage, with a considerable recurrence rate in locally advanced tumours. Complete resection in recurrences occurs only in a few cases. A new therapeutic strategy has emerged: the Hyperthermic Intrathoracic Chemotherapy (HITHOC), a high concentrated dose of...

Growth differentiation factor 15 as a biomarker for risk stratification in the ...

Growth Differentiation Factor 15 (GDF15) is an emerging biomarker that significantly increases during acute stress responses, such as infections, and is moderately elevated in chronic and inflammation-driven conditions. While evidence suggests that high levels of GDF15 in cardiac surgery are associated with worse outcomes, its utility as an evaluator of early postoperative complications remains unclear. This st...

Post-cardiotomy bronchopericardial fistula

We report a case of a 65 years-old woman submitted to an aortic and mitral valve replacement with mechanical prosthesis (St Jude 19mm and St Jude 21mm, respectively), who developed a postoperative cardiogenic shock, with necessity of mechanical support with extracorporeal membrane oxygenation and intra-aortic pump balloon.

Surgical aortic valve replacement in octogenarians: single-center perioperative...

Introduction and objectives: Aortic stenosis is the most common valvular heart disease. The number of octogenarians proposed for intervention is growing due to increased lifespan. In this manuscript we aim to evaluate perioperative outcome and long-term survival after surgical aortic valve replacement (SAVR) in octogenarians, comparing patients with low surgical risk (EuroscoreII <4%) with intermediate-high ris...

Post-cardiotomy Bronchopericardial Fistula