Abstract Mild cognitive impairment (MCI) is a neurocognitive deterioration of at least one of the following six cognitive domains in humans: complex attention, executive function, learning and memory, language, perceptual‑motor, and social cognition. Patients with chronic kidney disease are at an increased risk of developing this disorder, with serious implications for the patient, family, and society. In this ...
Abstract Introduction: The clinical management of secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD) stages G3‑G4 patients currently faces several challenges. Although the understanding of SHPT has increased exponentially in recent years, many aspects regarding its diagnosis and management in non‑dialysis G3‑G4 CKD remain elusive. Specifically, while it is known that SHPT is linked to vitamin ...
Abstract Chronic kidney disease (CKD) affects millions of people worldwide and is a major public health problem. Renin‑angiotensin system inhibitors are the backbone drugs for preventing CKD progression but have potential side effects, such as hyperkalemia or acute decrease in glomerular filtration rate, which can prevent physicians from starting the drugs, or even lead physicians to stop the drug when already ...
ABSTRACT Chronic kidney disease - mineral and bone disorders (CKD‑MBD) tends to improve or to change phenotypically in the post‑transplant period. Mineral and bone disorders post‑transplantation (MBD‑PT) seem to be associated with high fracture risk and cardiovascular morbidity, and so it is necessary to be aware of its presence to minimize the MBD‑PT impact. In this article we summarize the features of MBD‑PT.
ABSTRACT Chronic kidney disease is characterized by immune dysfunction that increases predisposition to infections, virus-associated cancers and impaired response to vaccination. The altered immune response is caused by impairment of both innate and adaptive immune systems, as well as other factors that are hallmarks of renal disease, such as uremia, malnutrition, chronic inflammation, mineral bone disease and ...
A successful peritoneal dialysis program follows evidence-based practice guidelines. In this first article we review the current guidelines on catheter insertion and on prevention of catheter-related infections, both subjects of extreme importance not only to initiate and also to maintain patients on peritoneal dialysis. The treatment of catheter-related infections is not part of the purpose of this article.
A successful peritoneal dialysis program depends on knowledge of the current recommendations and on evidence-based practice guidelines. In this second article, we review the dialysis prescription and the nutritional and cardiovascular management of peritoneal dialysis patients in the light of the existing guidelines advocated by different international societies.
Introduction and aims: The complement system may play a part in the pathogenesis of amyloid disorders. The primary aim of the study was to analyse the relationship between transthyretin renal amyloidosis (ATTR) and the complement system. The secondary aim was to find potential clinical and morphologic features in ATTR amyloidosis associated with complement activation. Methods: We performed a retrospective cohor...
Contrast agents are widely used in ambulatory and hospitalized patients, as a complement to imaging studies, improving diagnostic accuracy. Patients with chronic kidney disease are at increased risk for adverse events related to contrast administration. In this review, we will summarize the current evidence on this topic.