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Blue Light Exposure: Ocular Hazards and Prevention-A Narrative Review

Cougnard-Gregoire, Audrey; Merle, Bénédicte M. J.; Aslam, Tariq; Seddon, Johanna M.; Aknin, Isabelle; Klaver, Caroline C. W.; Garhöfer, Gerhard

Introduction: Exposure to blue light has seriously increased in our environment since the arrival of light emitting diodes (LEDs) and, in recent years, the proliferation of digital devices rich in blue light. This raises some questions about its potential deleterious effects on eye health. The aim of this narrative review is to provide an update on the ocular effects of blue light and to discuss the efficiency ...


Association of Systemic Medication Use with Glaucoma and Intraocular Pressure: ...

Vergroesen, Joëlle E.; Schuster, Alexander K.; Stuart, Kelsey V.; Asefa, Nigus G.; Cougnard-Grégoire, Audrey; Delcourt, Cécile; Schweitzer, Cédric

Purpose: To investigate the association of commonly used systemic medications with glaucoma and intraocular pressure (IOP) in the European population. Design: Meta-analysis of 11 population-based cohort studies of the European Eye Epidemiology Consortium. Participants: The glaucoma analyses included 143 240 participants and the IOP analyses included 47 177 participants. Methods: We examined associations of 4 ca...


Association of systemic medication use with glaucoma and intraocular pressure: ...

Vergroesen, Joëlle E.; Schuster, Alexander K.; Stuart, Kelsey V.; Asefa, Nigus G.; Cougnard-Grégoire, Audrey; Delcourt, Cécile; Schweitzer, Cédric

Purpose: To investigate the association of commonly used systemic medications with glaucoma and intraocular pressure (IOP) in the European population. Design: Meta-analysis of eleven population-based cohort studies of the European Eye Epidemiology (E3) consortium. Participants: A total of 143240 participants were included in the glaucoma analyses and 47177 participants in the IOP analyses. Methods: We examined ...


Exploring Consensus on Preventive Measures and Identification of Patients at Ri...

García-Layana, Alfredo; Garhöfer, Gerhard; Aslam, Tariq M.; Silva, Rufino; Delcourt, Cécile; Klaver, Caroline C. W.; Seddon, Johanna M.

Early identification of AMD can lead to prompt and more effective treatment, better outcomes, and better final visual acuity; several risk scores have been devised to determine the individual level of risk for developing AMD. Herein, the Delphi method was used to provide recommendations for daily practice regarding preventive measures and follow-up required for subjects at low, moderate, and high risk of AMD ev...


Adherence to a Mediterranean diet, lifestyle and age-related macular degenerati...

Raimundo, Miguel; Mira, Filipe; Cachulo, Maria da Luz; Barreto, Patrícia; Ribeiro, Luísa; Farinha, Cláudia; Laíns, Inês; Nunes, Sandrina; Alves, Dalila

Purpose To characterize the lifestyle and nutritional risk profile associated with the Mediterranean diet in a Portuguese population with and without age‐related macular degeneration (AMD). Methods Nested case–control study (n = 883) within the Coimbra Eye Study, including 434 subjects with AMD and 449 age‐ and sex‐matched subjects without AMD. All enrolled subjects underwent a full risk assessment, including l...


Vitamin D and Age-Related Macular Degeneration

Layana, Alfredo Garcia; Minnella, Angelo Maria; Garhöfer, Gerhard; Aslam, Tariq; Holz, Frank G; Leys, Anita; Silva, Rufino; Delcourt, Cécile

In recent years, the relationship between vitamin D and health has received growing attention from the scientific and medical communities. Vitamin D deficiencies have been repeatedly associated with various acute and chronic diseases, including age-related macular degeneration (AMD). Its active metabolite, 1α,25-dihydoxy vitamin D, acts as a modulator of cell proliferation, differentiation and apoptosis, and cu...


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