10 documents found, page 1 of 1
Chimeric Antigen Receptor T-Cell Therapy: Potentially Nephrotoxic?
Alferes,Daniela; Coelho,Inês; Ferreira,Hugo; Chuva,Teresa; Paiva,Ana; Chacim,Sérgio; Mariz,José Mário; Costa,José MaximinoAbstract Introduction: Chimeric antigen receptor (CAR) T‑cell therapy is an effective new treatment for hematologic malignancies. In this study, we aimed to characterize the acute kidney injury (AKI) and electrolyte disorders among adults with refractory and relapsed haematological malignancies treated with CAR‑T therapy and explore clinical outcomes. Methods: A retrospective, observational study was performed....
In-hospital and one-year mortality among patients with acute kidney injury and ...
Coelho,Inês; Chuva,Teresa; Ferreira,Hugo; Paiva,Ana; Costa,José M.ABSTRACT Hematological malignancies (HM) confer a high risk of acute kidney injury (AKI), which is associated with elevated morbi-mortality. The aim of this study was to identify the prognostic factors for in-hospital mortality and one-year mortality in this population. We conducted a single center, retrospective, observational cohort study of 101 in-hospital patients with AKI and HM between January 2015 and De...
Extracorporeal light chains removal - What role does this play in 2020?
Coelho,Inês; Ferreira,Hugo; Chuva,Teresa; Paiva,Ana; Maximino,JoséMultiple Myeloma (MM) is characterized by a neoplastic proliferation of plasma cell clones producing monoclonal immunoglobulin. Manifestations of the disease are heterogenous and include dialysis-requiring acute kidney injury (AKI) caused mainly by cast nephropathy (CN). It is known that early and rapid decrease in serum free light chains (sFLC) levels is particularly important for renal recovery, which has led...
Hemodialysis arteriovenous fistula outcomes in elderly patients: a single-centr...
Ferreira,Hugo; Diniz,Hugo; Martins,Patrícia; Coentrão,LuísThe cohort of older age pre-dialysis patients is growing steadily. However, Fistula First may not always be the best strategy due to poorer arteriovenous fistula outcomes in this population. This retrospective cohort study included data from 157 predialysis patients who underwent fistula placement in our centre. Their mean age was 68.1±12.4 years. 64.3% were male and 53.5% were diabetic. The median nephrology...
Occult Metastatic Melanoma Presenting as an Acute Coronary Syndrome
Velho,Tiago R.; Junqueira,Nádia; Sena,André; Ferreira,Hugo; Carvalheiro,Catarina; Guerra,Nuno; Gallego,Javier; Nobre,ÂngeloAbstract Melanoma is a tumor that virtually involves any tissue and commonly metastasizes to the heart. It is usually not diagnosed because of the absent/nonspecific cardiac signs and symptoms. Herein, we present a case of a 41-year-old man without any cardiovascular risk factor, admitted to the emergency room with chest pain, diagnosed with a myocardial infarction. Due to the presence of a mass adjacent to the...
Gravidez após transplante renal: interação entre a gestação e o enxerto
Ferreira,Cátia; Ferreira,Hugo; Machado,Ana Paula; Santos,Joana; Montenegro,NunoOverview and aims: Kidney transplantation has brought a new hope to women with end stage renal disease (ESRD) who wish to become pregnant, as it can improve the reproductive function and restore fertility. A successful pregnancy after kidney transplant is possible, at expenses of high rates of maternal and fetal morbidity. The objective of the study is to investigate the impact of renal transplantation in obste...
Production of Piptadenia stipulacea (Benth.) Ducke seedlings irrigated with fis...
Almeida,João P. N. de; Freitas,Rômulo M. O. de; Nogueira,Narjara W.; Oliveira,Francisco de A. de; Ferreira,Hugo; Leite,Moadir de S.ABSTRACT The objective of this study was to evaluate the growth of ‘jurema-branca’ seedlings (Piptadenia stipulacea (Benth.) Ducke.), irrigated with effluent from fish farming in order to meet the nutritional demand in the initial growth stage. The treatments consisted in the dilution of fish farming wastewater in different concentrations (0, 25, 50, 75 and 100%) with supply water. Seeds were sown in 0.9-L poly...
Chronic myelomonocytic leukaemia: a presentation with rare extramedullary invol...
Borges,Tiago; Rêgo,Inês; Badas,Jenny; Marques,Sofia; Ferreira,Hugo; Pinto,Ricardo; Oliveira,JorgeA 74-year-old male with a recent diagnosis of chronic myelomonocytic leukaemia (CMML) was admitted for rapidly progressive renal failure (RPRF), associated with gait impairment due to muscle weakness and pain in the lower limbs. After exclusion of pre-renal and post-renal causes of RPRF, the workup revealed monocytosis, high levels of inflammatory markers, hypergammaglobulinaemia, nephrotic proteinuria and high...
Hemodialysis Reliable Outflow (HeRO) Graft device: a lifesaving solution in mul...
Vieira,Miguel Bigotte; Ferreira,Tiago; Fortes,Alice; Martins,Pedro; Ministro,Augusto; Ferreira,Hugo; Silva,Hugo; Amaral,Tiago; Resina,CristinaThe increasing prevalence of end-stage chronic kidney disease associated with advances in treatment is expected to lead to improved survival rates of chronic haemodialysis patients in Portugal. Establishing and maintaining vascular access patency is becoming a challenging issue in these patients. We present a case report of a multiple vascular access failure patient to whom a novel vascular access device was im...
Growth of young Tabebuia aurea seedlings under irrigation with wastewater from ...
Pinto,José R. de S.; Freitas,Rômulo M. O. de; Leite,Tiago de S.; Oliveira,Francisco de A. de; Ferreira,Hugo; Leite,Moadir de S.ABSTRACT This study aimed to evaluate the growth of young Tabebuia aurea seedlings irrigated with different concentrations of wastewater from fish farming. The experiment was conducted in a seedling nursery, from June to August 2013. The treatments consisted of five concentrations of wastewater from fish farming diluted in freshwater (0, 25, 50, 75 and 100% of wastewater). Plant height, stem diameter and plant ...