2 documents found, page 1 of 1
Sex differences on solid organ histological characteristics after brain death1
Simão,Raif Restivo; Ferreira,Sueli Gomes; Kudo,Guilherme Konishi; Armstrong Junior,Roberto; Silva,Luiz Fernando Ferraz da; Sannomiya,PaulinaPURPOSE: To investigate gender differences in the evolution of the inflammatory process in rats subjected to brain death (BD). METHODS: Adult Wistar rats were divided into three groups: female; ovariectomized female; and male rats. BD was induced using intracranial balloon inflation and confirmed by maximal pupil dilatation, apnea, absence of reflex, and drop of mean arterial pressure. Six hours after BD, histo...
Effect of N-acetylcysteine on pulmonary cell death in a controlled hemorrhagic ...
Saad,Paulo Fernandes; Saad,Karen Ruggeri; Oliveira Filho,Luiz Dantas de; Ferreira,Sueli Gomes; Koike,Marcia Kiyomi; Montero,Edna Frasson de SouzaPURPOSE: To evaluate the effect of N-acetylcysteine (NAC) combined with fluid resuscitation on pulmonary cell death in rats induced with controlled hemorrhagic shock (HS). METHODS: Two arteries (MAP calculation and exsanguination) and one vein (treatments) were catheterized in 22 anesthetized rats. Two groups of male albino rats were induced with controlled HS at 35mmHg MAP for 60 min. After this period, the RL...