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Malignant peripheral nerve sheath tumors (MPNST) are uncommon, biologically challenging soft tissue sarcomas. The definitive treatment of these tumors is extremely challenging. In 50% of cases, these tumors are associated with type I neurofibromatosis, but in some cases, the cause can be previous treatment with radiotherapy. The present article pretends to report a clinical case of a radiation-induced MPNST sub...
Introduction: Breast cancer biological subtype has an important impact in the definition of the treatment strategy and the prognosis. However, the influence of neoadjuvant chemotherapy in the immunohistochemistry profile of the tumor is not well clarified. This study aims to evaluate the incidence of immunohistochemistry profile changes after neoadjuvant chemotherapy and the impact of these changes in adj...