29 documents found, page 1 of 3

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Lidocaine-Induced Central Nervous System Toxicity During Implantable Cardiovert...

Nunes Silva, M; Ferro, A; Fragata, I

Lidocaine, a local anesthetic, is commonly used in various medical procedures. Despite its widespread use, most physicians are not familiar with the life threatening presentation of lidocaine toxicity and its treatment. Our case demonstrates successful management of local lidocaine-induced systemic toxicity in a 53-year-old female during insertion of an implantable cardioverter defibrillator. Our goal was to ra...


Can serum endoglin be used to improve the diagnostic performance in prostate ca...

Pina, F; Ferro, A; Botelho, F; Manso, M; Dias, N; Figueiredo, G; Pereira, P; Dinis, P; Barros, H; Lunet, N

Purpose: New biomarkers may contribute to avoid unnecessary biopsies resulting from the suboptimal performance of prostate-specific antigen (PSA) testing. This study aimed to assess serum endoglin as a prostate cancer (PCa) diagnostic tool among biopsy candidates. Methods: A total of 262 consecutive patients referred for prostate biopsy based on abnormal digital rectal examination and/or elevated total PSA (tPS...


Fruits and vegetables intake and gastric cancer risk: A pooled analysis within ...

Ferro, A; Costa, AR; Morais, S; Bertuccio, P; Rota, M; Pelucchi, C; Hu, J; Johnson, KC; Zhang, ZF; Palli, D; Ferraroni, M; Yu, GP; Bonzi, R

A low intake of fruits and vegetables is a risk factor for gastric cancer, although there is uncertainty regarding the magnitude of the associations. In our study, the relationship between fruits and vegetables intake and gastric cancer was assessed, complementing a previous work on the association betweenconsumption of citrus fruits and gastric cancer. Data from 25 studies (8456 cases and 21 133 controls) with...


Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) pro...

Ferro, A; Rosato, V; Rota, M; Costa, AR; Morais, S; Pelucchi, C; Johnson, KC; Hu, J; Palli, D; Ferraroni, M; Zhang, ZF; Bonzi, R; Yu, GP; Peleteiro, B

The consumption of processed meat has been associated with noncardia gastric cancer, but evidence regarding a possible role of red meat is more limited. Our study aims to quantify the association between meat consumption, namely white, red and processed meat, and the risk of gastric cancer, through individual participant data meta-analysis of studies participating in the “Stomach cancer Pooling (StoP) Project”....


Education and gastric cancer risk-An individual participant data meta-analysis ...

Rota, M; Alicandro, G; Pelucchi, C; Bonzi, R; Bertuccio, P; Hu, J; Zhang, ZF; Johnson, KC; Palli, D; Ferraroni, M; Yu, GP; Galeone, C; López-Carrillo, L

Low socioeconomic position (SEP) is a strong risk factor for incidence and premature mortality from several cancers. Our study aimed at quantifying the association between SEP and gastric cancer (GC) risk through an individual participant data meta-analysis within the “Stomach cancer Pooling (StoP) Project”. Educational level and household income were used as proxies for the SEP. We estimated pooled odds ratios...


Sex differences in the prevalence of Helicobacter pylori infection: an individu...

Ferro, A; Morais, S; Pelucchi, C; Dierssen-Sotos, T; Martín, V; López-Carrillo, L; Malekzadeh, R; Tsugane, S; Hamada, GS; Hidaka, A

Background Helicobacter pylori (H. pylori) infection is more frequent among men, though the magnitude of the association might be inaccurate due to potential misclassification of lifetime infection and publication bias. Moreover, infection is common, and most studies are cross-sectional. Thus, prevalence ratios (PRs) may be easier to interpret than odds ratios (ORs). Aim The aim of this study was to quantify th...


Cancer incidence in Mozambique in 2015-2016: data from the Maputo Central Hospi...

Carrilho, C; Fontes, F; Tulsidás, S; Lorenzoni, C; Ferro, J; Brandão, M; Ferro, A; Lunet, N

There is scarce information on cancer incidence in Mozambique. We aimed to describe cancer incidence data from the Cancer Registry of the Maputo Central Hospital (MCH) in 2015–2016, for Maputo City dwellers, and to compare the incidence rates with those observed in 1956–1961. Cancers with incidence data in 2015–2016 were identified by the Cancer Registry of the MCH. Crude and age-standardized incident rates (AS...


Citrus fruit intake and gastric cancer: The stomach cancer pooling (StoP) proje...

Bertuccio, P; Alicandro, G; Rota, M; Pelucchi, C; Bonzi, R; Galeone, C; Bravi, F; Johnson, KC; Hu, J; Palli, D; Ferraroni, M; López-Carrillo, L

Diets rich in vegetables and fruit have been associated with reduced risk of gastric cancer, and there is suggestive evidence that citrus fruits have a protective role. Our study aimed at evaluating and quantifying the association between citrus fruit intake and gastric cancer risk. We conducted a one-stage pooled analysis including 6,340 cases and 14,490 controls from 15 case–control studies from the stomach c...


S100P is a molecular determinant of E-cadherin function in gastric cancer

Carneiro, P; Moreira, AM; Figueiredo, J; Barros, R; Oliveira, P; Fernandes, MS; Ferro, A; Almeida, R; Oliveira, C; Carneiro, F; Schmitt, F; Paredes, J

Background: E-cadherin has been awarded a key role in the aetiology of both sporadic and hereditary forms of gastric cancer. In this study, we aimed to identify molecular interactors that influence the expression and function of E-cadherin associated to cancer. Methods: A data mining approach was used to predict stomach-specific candidate genes, uncovering S100P as a key candidate. The role of S100P was evaluat...


Smoking and Helicobacter pylori infection: an individual participant pooled ana...

Ferro, A; Morais, S; Pelucchi, C; Aragonés, N; Kogevinas, M; López-Carrillo, L; Malekzadeh, R; Tsugane, S; Hamada, GS; Hidaka, A; Hernández-Ramírez, RU

Smoking has been associated with acquisition and increased persistence of Helicobacter pylori infection, as well as with lower effectiveness of its eradication. A greater prevalence of infection among smokers could contribute to the increased risk for gastric cancer. We aimed to estimate the association between smoking and seropositivity to H. pylori through an individual participant data pooled analysis using ...


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