24 documents found, page 1 of 3

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Decompressive Surgery in Cerebral Venous Sinus Thrombosis Due to Vaccine‐Induce...

Krzywicka, K; Aguiar de Sousa, D; Cordonnier, C; Bode, F; Field, T; Michalski, D; Pelz, J; Skjelland, M; Wiedmann, M; Zimmermann, J; Wittstock, M

Background and purpose: Cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia (CVST-VITT) is an adverse drug reaction occurring after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. CVST-VITT patients often present with large intracerebral haemorrhages and a high proportion undergoes decompressive surgery. Clinical characteristics, therapeutic manag...


Risk Factors for Breast Cancer, Overall and by Tumor Subtype, among Women from ...

Brandão, M; Guisseve, A; Damasceno, A; Bata, G; Silva-Matos, C; Alberto, M; Ferro, J; Garcia, C; Zaqueu, C; Lorenzoni, C; Leitão, D; Soares, O

Background: Breast cancer incidence is rising in Africa, but there are scare data regarding risk factors in this region. We assessed the relation between risk factors and the occurrence of breast cancer, overall and by tumor subtype in women from Mozambique. Methods: The associations between education, number of births, height, weight, body mass index (BMI), and breast cancer risk among 138 cases (participants ...


Survival Impact and Cost-Effectiveness of a Multidisciplinary Tumor Board for B...

Brandão, M; Guisseve, A; Bata, G; Firmino-Machado, J; Alberto, M; Ferro, J; Garcia, C; Zaqueu, C; Jamisse, A; Lorenzoni, C; Piccart-Gebhart, M

Background Despite the international endorsement of multidisciplinary tumor boards (MTBs) for breast cancer care, implementation is suboptimal worldwide, and evidence regarding their effectiveness in developing countries is lacking. We assessed the impact on survival and the cost-effectiveness of implementing an MTB in Mozambique, sub-Saharan Africa. Materials and Methods This prospective cohort study included ...


Characteristics and Outcomes of Patients With Cerebral Venous Sinus Thrombosis ...

Sánchez van Kammen, M; Aguiar de Sousa, D; Poli, S; Cordonnier, C; Heldner, M; van de Munckhof, A; Krzywicka, K; van Haaps, T; Ciccone, A; Middeldorp, S

Importance: Thrombosis with thrombocytopenia syndrome (TTS) has been reported after vaccination with the SARS-CoV-2 vaccines ChAdOx1 nCov-19 (Oxford-AstraZeneca) and Ad26.COV2.S (Janssen/Johnson & Johnson). Objective: To describe the clinical characteristics and outcome of patients with cerebral venous sinus thrombosis (CVST) after SARS-CoV-2 vaccination with and without TTS. Design, setting, and participants: ...


Neoplastic and pre-neoplastic lesions of the oesophagus and gastro-oesophageal ...

Grillo, F; Mastracci, L; Saragoni, L; Vanoli, A; Limarzi, F; Gullo, I; Ferro, J; Paudice, M; Parente, P; Fassan, M

Oesophageal and gastro-oesophageal junction (GOJ) neoplasms, and their predisposing conditions, may be encountered by the practicing pathologist both as biopsy samples and as surgical specimens in daily practice. Changes in incidence of oesophageal squamous cell carcinomas (such as a decrease in western countries) and in oesophageal and GOJ adenocarcinomas (such as a sharp increase in western countries) are bei...


Breast cancer subtypes: implications for the treatment and survival of patients...

Brandão, M; Guisseve, A; Bata, G; Alberto, M; Ferro, J; Garcia, C; Zaqueu, C; Lorenzoni, C; Leitão, D; Come, J; Soares, O; Gudo-Morais, A; Schmitt, F

Background. Data regarding breast cancer epidemiology, treatment and survival in Africa are scarce. We aimed to assess the distribution of breast cancer subtypes in Mozambique and its impact on patients’ treatment and survival. The concordance of biomarker assessment between cytological and histological samples was also evaluated. Methods. Prospective cohort study including 210 patients diagnosed between Januar...


Precancerous lesions of the stomach, gastric cancer and hereditary gastric canc...

Gullo, I; Grillo, F; Mastracci, L; Vanoli, A; Carneiro, F; Saragoni, L; Limarzi, F; Ferro, J; Parente, P; Fassan, M

Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently diagnosed malignancy and the third leading cause of cancer related death. Gastric carcinogenesis is a multistep and multifactorial process and is the result of the complex interplay between genetic susceptibility and environmental factors. The identification of predisposing conditions and of precancerous lesions is the ba...


Cancer incidence in Mozambique in 2015-2016: data from the Maputo Central Hospi...

Carrilho, C; Fontes, F; Tulsidás, S; Lorenzoni, C; Ferro, J; Brandão, M; Ferro, A; Lunet, N

There is scarce information on cancer incidence in Mozambique. We aimed to describe cancer incidence data from the Cancer Registry of the Maputo Central Hospital (MCH) in 2015–2016, for Maputo City dwellers, and to compare the incidence rates with those observed in 1956–1961. Cancers with incidence data in 2015–2016 were identified by the Cancer Registry of the MCH. Crude and age-standardized incident rates (AS...


Early EEG Predicts Poststroke Epilepsy

Bentes, C; Martins, H; Peralta, AR; Morgado, C; Casimiro, C; Franco, AC; Fonseca, AC; Geraldes, R; Canhão, P; Pinho e Melo, T; Paiva, T; Ferro, J

Objective: Electroencephalography (EEG) can identify biomarkers of epileptogenesis and ictogenesis. However, few studies have used EEG in the prediction of poststroke seizures. Our primary aim was to evaluate whether early EEG abnormalities can predict poststroke epilepsy. Methods: A prospective study of consecutive acute anterior circulation ischemic stroke patients, without previous epileptic seizures, who we...


Kaposi sarcoma incidence in Mozambique: national and regional estimates

Meireles, P; Albuquerque, G; Vieira, M; Foia, S; Ferro, J; Carrilho, C; Lunet, N

Kaposi sarcoma is expressed in four clinical variants, all associated with human herpes virus type 8 infection, namely, classic, endemic, immunosuppression-related and AIDS-related. The latter currently accounts for most of the burden of Kaposi sarcoma in sub-Saharan Africa, reflecting the frequency of HIV infection and its management. We aimed to estimate the incidence of Kaposi sarcoma in Mozambique and in it...


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