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Multidisciplinary Approaches and Molecular Diagnostics in New-Onset Refractory ...

Batarda Sena, Pedro Manuel; Ferro, Margarida; Alves Cabrita, Joana; Pontinha, Carlos; Mestre, Ana; Oliveira, Mário; Bento, Luis

The diagnosis and management of complex neurological conditions such as New-Onset Refractory Status Epilepticus (NORSE) and central nervous system (CNS) infections caused by non-tuberculous mycobacteria (NTM) pose substantial difficulties in intensive care units (ICUs). This article combines a case report and a literature review that explores the diagnostic dilemmas and therapeutic strategies for these critical...


Clinical Practice Protocol for Management of Women of Childbearing-Age with Epi...

Ferro, Margarida; Serôdio, Miguel; Beja, Mariana; Menezes Cordeiro, Inês; Parra, Joana; Sá, Francisca

Women of childbearing-age with epilepsy presents with challenges in prevention, planning and orientation of gestation and post-partum. Gestation in women with epilepsy represents 0.3% to 0.5% of all pregnancies, and one third of women with epilepsy is in childbearing-age. Epilepsy may be associated with serious complications in pregnant women, with a higher risk of congenital malformations, intrauterine growth ...

Date: 2023   |   Origin: SINAPSE

The Mediterranean diet, and not dietary inflammatory index, is associated with ...

Charneca, Sofia; Ferro, Margarida; Vasques, João; Carolino, Elisabete; Martins-Martinho, Joana; Duarte-Monteiro, Ana Margarida; Dourado, Eduardo

Purpose: To assess the relationship between adherence to the Mediterranean Diet (MD) /individual Dietary Inflammatory Index (DII) and disease activity, disease impact, and functional status in Rheumatoid Arthritis (RA) patients. Methods: RA patients followed at a hospital in Lisbon, Portugal, were recruited. DII was calculated using dietary intake data collected with a food frequency questionnaire (FFQ). Adhere...


The Mediterranean diet, and not dietary inflammatory index, is associated with ...

Charneca, Sofia; Ferro, Margarida; Vasques, João; Carolino, Elisabete; Martins-Martinho, Joana; Duarte-Monteiro, Ana Margarida; Dourado, Eduardo

Purpose: To assess the relationship between adherence to the Mediterranean Diet (MD) /individual Dietary Inflammatory Index (DII) and disease activity, disease impact, and functional status in Rheumatoid Arthritis (RA) patients. Methods: RA patients followed at a hospital in Lisbon, Portugal, were recruited. DII was calculated using dietary intake data collected with a food frequency questionnaire (FFQ). Adhere...


A case of trigeminal malignant melanotic nerve sheath tumor in the wide spectru...

Rachão, Augusto; Ferro, Margarida; Roque, Rafael; Rainha Campos, Alexandre; Pimentel, José

We report the case of a 42-year-old male, without any other personal or familiar relevant background, who was referred to a neurosurgery outpatient clinic due to a yearlong altered right facial sensitivity with paresthesia. Facial hypoesthesia in V1 and V2 divisions of the right trigeminal nerve was noticed. No other deficits were evidenced, and the remaining objective examination was unremarkable, namely for c...


Probiotic supplementation for Rheumatoid Arthritis: a promising adjuvant therap...

Ferro, Margarida; Charneca, Sofia; Dourado, Eduardo; Guerreiro, Catarina Sousa; Fonseca, João Eurico

Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease that ultimately leads to joint destruction and functional disability. Although the exact etiology of RA is not fully understood, it is well established that gut microbiota (GM) plays a vital role in the pathogenesis of RA, with accumulating evidence suggesting that gut dysbiosis induces a chronic inflammatory response that may be linked...


Diet as a modulator of intestinal microbiota in rheumatoid arthritis

Dourado, Eduardo; Ferro, Margarida; Guerreiro, Catarina Sousa; Fonseca, João Eurico

Rheumatoid arthritis (RA) is a chronic immune-driven inflammatory disease characterised by synovial inflammation, leading to progressive cartilage and bone destruction, impacting patients’ functional capacity and quality of life. Patients with RA have significant differences in gut microbiota composition when compared to controls. Intestinal dysbiosis influences the intestinal barrier strength, integrity and fu...


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