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Which imaging outcomes for axSpA are most sensitive to change?

Sepriano, Alexandre; Ramiro, Sofia; van der Heijde, Désirée; Dougados, Maxime; Claudepierre, Pascal; Feydy, Antoine; Reijnierse, Monique

OBJECTIVE: To compare the sensitivity to change of different imaging scoring methods in patients with early axial spondyloarthritis (axSpA). METHODS: Patients from the DESIR cohort fulfilling the ASAS axSpA criteria were included. Radiographs and MRI of the sacroiliac joints (SIJ) and spine were obtained at baseline, 1, 2 and 5 years. Each image was scored by 2 or 3 readers in 3 separate 'reading-waves'. The ra...


Spinal Radiographic Progression in Early Axial Spondyloarthritis

Ramiro, Sofia; van der Heijde, Désirée; Sepriano, Alexandre; van Lunteren, Miranda; Moltó, Anna; Feydy, Antoine; d'Agostino, Maria Antonietta

Objective: To analyze the progression of spinal radiographic damage in patients with early axial spondyloarthritis (SpA). Methods: Axial SpA patients from the DESIR (Devenir des Spondylarthropathies Indifférenciées Récentes) cohort with 5-year spinal (cervical and lumbar) radiographs available (n = 549) were included. Two- and 5-year modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) progression and dev...


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