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Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabo...
Almeida, João F; Marques, Matilde S.; Oliveira, Vanessa; Egas, Conceição; Mil-Homens, Dalila; Viana, Romeu; Cleary, Daniel F. R.; Huang, Yusheng MMarine microbiomes are prolific sources of bioactive natural products of potential pharmaceutical value. This study inspected two culture collections comprising 919 host-associated marine bacteria belonging to 55 genera and several thus-far unclassified lineages to identify isolates with potentially rich secondary metabolism and antimicrobial activities. Seventy representative isolates had their genomes mined f...
Third generation cephalosporin-resistant Klebsiella pneumoniae thriving in pati...
Rocha, Jaqueline; Ferreira, Catarina; Mil-Homens, Dalila; Busquets, Antonio; Fialho, Arsénio M; Henriques, Isabel; Gomila, Margarita; Manaia, Célia M.Klebsiella pneumoniae are ubiquitous bacteria and recognized multidrug-resistant opportunistic pathogens that can be released into the environment, mainly through sewage, where they can survive even after wastewater treatment. A major question is if once released into wastewater, the selection of lineages missing clinically-relevant traits may occur. Wastewater (n = 25) and clinical (n = 34) 3rd generation ceph...