5 documents found, page 1 of 1
Metaplastic carcinoma of the breast: case series of a single centre
Fialho, M. Pinto; Gonçalves, L.; Ruivo, L.; Gradil, A.; Correia, L.Background & objectives: Metaplastic carcinoma breast cancer (MpBC) is a rare and heterogeneous group of invasive breast carcinomas. Despite some studies and case reports data are currently limited. Our work aims to evaluate the clinicopathological features and the prognosis of MpBC patients. Methods: Retrospective unicentric study of MpBC diagnosed from January 2000 to February 2024. Pathological reports were ...
Modified auramine-rhodamine stain contribution to identify mycobacterium tuberc...
Ruivo, L.; Fialho, M. Pinto; Santos, H. S.; Tavares, J. A.; Ferreira, C.Background & objectives: Mycobacterium tuberculosis (MT) infection often causes multiple organ granulomatous disease. Suspicious lesions are often biopsied to exclude malignancy. Ziehl-Neelsen (ZN) staining is the histological standard diagnostic tool for MT, although auramine-rhodamine (AR) appears to have better detection ratios. Methods: We evaluated all biopsies with suspected clinical tuberculosis (combine...
Cutaneous non-tuberculous mycobacteria infection: a case report and literature ...
Fialho, M. Pinto; Carvalho, M. M.; Catarino, A. M.; Casanova, S. R.; Sampaio, R.Background & objectives: Non-tuberculous mycobacteria (NTM) are often overlooked as opportunistic agents causing cutaneous infections. While histological findings may resemble cutaneous tuberculosis, treatment and clinical management differ significantly. We present a case of NTM skin infection and a literature review. Methods: A 62-year-old female with autoimmune hepatitis, on immunosuppression, received a cor...
Sebaceous carcinoma in a mature cystic teratoma of the ovary
Fialho, M. Pinto; Gradil, A.; Ferreira, C.; Lérias, S.Background & objectives: Sebaceous carcinoma originating within an ovarian mature cystic teratoma (MCT) is an extremely rare entity. To the best of our knowledge, less than 14 cases have been reported in the literature. Methods: We report a case of a sebaceous carcinoma arising within a mature teratoma. Results: An 83-year-old female presented with urinary retention symptoms. A pelvic MRI scan revealed a left o...
Tumour infiltrating lymphocytes characterization in advanced non-small cell lun...
Ruivo, L.; Fialho, M. Pinto; Baptista, D.; Filipe, J.Background & objectives: Tumour-infiltrating lymphocytes (TILs) may have an impact on prognosis in non-small cell lung cancer (NSCLC) and may affect the efficacy of treatment. We aim to characterize TILs in advanced NSCLC with PD-L1 score>50%, treated with first-line immune checkpoint inhibitors. Methods: We performed a single-centre retrospective study. Patients diagnosed with advanced NSCLC with PD-L1>50%, fr...