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Is the proteome of bronchoalveolar lavage extracellular vesicles a marker of ad...

Carvalho, AS; Moraes, MCS; Na, CH; Fierro-Monti, I; Henriques, A; Zahedi, S; Bodo, C; Tranfield, EM; Sousa, AL; Farinho, A; Rodrigues, LV; Pinto, P

Acellular bronchoalveolar lavage (BAL) proteomics can partially separate lung cancer from non-lung cancer patients based on principal component analysis and multivariate analysis. Furthermore, the variance in the proteomics data sets is correlated mainly with lung cancer status and, to a lesser extent, smoking status and gender. Despite these advances BAL small and large extracellular vehicles (EVs) proteomes r...


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