14 documents found, page 1 of 2

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Modified Mediterranean diet effects on Parkinson's disease (MED-PARK)

Pirovano, Elenamaria; Marino, Franca; Rossi, Elena; Gennari, Andrea; Rasini, Emanuela; Uslenghi, Margherita; Figueira, Inês; Iacoviello, Licia

Publisher Copyright: © Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.; INTRODUCTION: Only symptomatic treatments are available for patients with Parkinson's disease (PD), the second most common chronic neurodegenerative disease worldwide, and it is therefore imperative to identify disease-modifying interventions t...


“Recommendations for clinical study protocols for immune and inflammatory profi...

Muñoz-Delgado, Laura; Williams-Gray, Caroline H.; Garraux, Gaetan; Clemente, Diego; Çakmak, Özgür Öztop; Greenland, Julia C.; Figueira, Inês

Publisher Copyright: © The Author(s) 2025.; Growing evidence supports the importance of immune processes in Parkinson’s disease (PD). However, there is a need to improve the quality of observational clinical studies investigating the role of immunity in PD. In this context, an expert panel from the COST Action IMMUPARKNET (CA21117) aimed to develop guidance recommendations for conducting optimal immune profilin...


Associação entre os fatores socioeconómicos da família, o excesso de peso e a p...

Figueira, Inês; Rito, Ana

A nível global, a obesidade infantil, os hábitos alimentares e as desigualdades socioeconómicas representam um desafio contemporâneo de saúde pública. O principal objetivo deste estudo é caraterizar as associações entre os fatores socioeconómicos da família com a perceção do consumo de alimentos de elevada densidade energética durante a pandemia em comparação com o período pré-pandemia e com a prevalência de ex...


Strategies for the engagement of youth in health-related activities in Portugal...

Mendes, Sofia; Figueira, Inês; Rito, Ana

Introduction: The lack of attention paid by policymakers to the views and role of young people in societal matters, including health, has been a contributor factor for the poor youth involvement in the development of health-related policies. The CO-CREATE (CC) project aims to collaborate with adolescents across Europe in developing policy ideas that contribute to overweight and obesity prevention. Aim: Present ...


Childhood Obesity Surveillance Initiative: COSI Portugal 2022

Rito, Ana; Mendes, Sofia; Figueira, Inês; Faria, Maria do Carmo; Carvalho, Rita; Santos, Teresa; Cardoso, Susana; Feliciano, Elsa; Silvério, Rosa

O Childhood Obesity Surveillance Initiative (COSI)/Organização Mundial da Saúde (OMS) é o sistema europeu de vigilância nutricional infantil coordenado pelo Gabinete Regional Europeu da OMS. Tem como principal objetivo criar uma rede sistemática de recolha, análise, interpretação e divulgação de informação descritiva sobre as caraterísticas do estado nutricional infantil de crianças dos 6 aos 8 anos, que se tra...


Dietary (Poly)phenols in Traumatic Brain Injury

Carecho, Rafael; Carregosa, Diogo; Ratilal, Bernardo Oliveira; Figueira, Inês; Ávila-Gálvez, María Ángeles; Nunes Dos Santos, Claudia

Funding Information: This research was funded by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program under grant agreement No 804229. iNOVA4Health Research Unit (LISBOA-01-0145-FEDER-007344), which is co-funded by Fundação para a Ciência e Tecnologia (FCT)/Ministério da Ciência e do Ensino Superior, through national funds, and by FEDER under the PT2020 Par...


Dietary (poly)phenols in traumatic brain injury

Carecho, Rafael; Carregosa, Diogo; Ratilal, Bernardo; Figueira, Inês; Ávila-Gálvez, Maria Angeles; dos Santos, Cláudia Nunes

Traumatic brain injury (TBI) remains one of the leading causes of death and disability in young adults worldwide. Despite growing evidence and advances in our knowledge regarding the multifaceted pathophysiology of TBI, the underlying mechanisms, though, are still to be fully elucidated. Whereas initial brain insult involves acute and irreversible primary damage to the brain, the processes of subsequent seconda...


Alterações no consumo alimentar e outros comportamentos relacionados com a alim...

Baleia, Joana; Pirata, Catarina; Mendes, Sofia; Figueira, Inês; Martins, Fátima; Rito, Ana Isabel

O confinamento obrigatório e o encerramento das escolas durante a pandemia da COVID-19 afetaram as rotinas e estilos de vida das crianças, com impacto na sua saúde. Este trabalho pretende identificar as mudanças no consumo e comportamentos alimentares durante o primeiro confinamento em contexto da pandemia da COVID-19 em 2020, entre crianças do 1.º Ciclo do Ensino Básico (EB). Este estudo transversal decorreu d...


Behind Brain Metastases Formation: Cellular and Molecular Alterations and Blood...

Pereira, Joana; Garcia, Ana Rita; Figueira, Inês; Malhó, Rui; Brito, Maria Alexandra

Breast cancer (BC) brain metastases is a life-threatening condition to which accounts the poor understanding of BC cells’ (BCCs) extravasation into the brain, precluding the development of preventive strategies. Thus, we aimed to unravel the players involved in the interaction between BCCs and blood–brain barrier (BBB) endothelial cells underlying BBB alterations and the transendothelial migration of malignant ...


5-(Hydroxyphenyl)-γ-Valerolactone-Sulfate, a Key Microbial Metabolite of Flavan...

Angelino, Donato; Carregosa, Diogo; Domenech-Coca, Cristina; Savi, Monia; Figueira, Inês; Brindani, Nicoletta; Jang, Saebyeol; Lakshman, Sukla

Phenolic compounds have been recognized as promising compounds for the prevention of chronic diseases, including neurodegenerative ones. However, phenolics like flavan-3-ols (F3O) are poorly absorbed along the gastrointestinal tract and structurally rearranged by gut microbiota, yielding smaller and more polar metabolites like phenyl-γ-valerolactones, phenylvaleric acids and their conjugates. The present work i...


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