19 documents found, page 1 of 2

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Guidelines for the Management of Center-Involving Diabetic Macular Edema: Treat...

Figueira, J; Henriques, J; Carneiro, A; Marques-Neves, C; Flores, R; Castro-Sousa, JP; Meireles, A; Gomes, N; Nascimento, J; Amaro, M; Silva, R

Diabetic macular edema (DME) is the main cause of visual impairment associated with diabetic retinopathy (DR) and macular laser, during approximately three decades, and was the single treatment option. More recently, intravitreous injections of anti-angiogenics and corticosteroids modified the treatment paradigm associated with significant vision improvements. Nevertheless, not all patients respond satisfactori...


A Nonrandomized, Open-Label, Multicenter, Phase 4 Pilot Study on the Effect and...

Figueira, J; Henriques, J; Amaro, M; Rosas, V; Alves, D; Cunha-Vaz, J

PURPOSE: The aim of this study was to assess the effectiveness and safety of ILUVIEN® in patients with chronic diabetic macular edema (DME) who were insufficiently responsive to prior therapies. METHODS: This is a prospective, nonrandomized, multicenter, open-label, phase 4 pilot study assessing the effectiveness and safety of ILUVIEN® involving 12 patients insufficiently responsive to available therapies. Asse...


A Nonrandomized, Open-Label, Multicenter, Phase 4 Pilot Study on the Effect and...

Figueira, J; Henriques, J; Amaro, M; Rosas, V; Alves, D; Cunha-Vaz, J

PURPOSE: The aim of this study was to assess the effectiveness and safety of ILUVIEN® in patients with chronic diabetic macular edema (DME) who were insufficiently responsive to prior therapies. METHODS: This is a prospective, nonrandomized, multicenter, open-label, phase 4 pilot study assessing the effectiveness and safety of ILUVIEN® involving 12 patients insufficiently responsive to available therapies. Asse...


Long-Term Management of RAP Lesions in Clinical Practice: Treatment Efficacy an...

Marques, MF; Marques, JP; Gil, J; Costa, J; Almeida, E; Cachulo, Mz; Pires, I; Figueira, J; Silva, R

PURPOSE: To evaluate the long-term efficacy of ranibizumab in the treatment of retinal angiomatous proliferation (RAP) and to identify predictors of functional outcome. METHODS: Retrospective case series comprised 79 eyes of 68 consecutive patients with RAP followed up ≥36 months. Primary end-points were best-corrected visual acuity (BCVA) and central macular thickness (CMT) variation at 36 months and at the la...


Sequential Morphological Changes in the CNV Net after Intravitreal Anti-VEGF Ev...

Marques, JP; Costa, JF; Marques, M; Cachulo, ML; Figueira, J; Silva, R

PURPOSE: To assess and describe sequential morphological changes in the choroidal neovascularization (CNV) net using optical coherence tomography angiography (OCTA) in patients undergoing treatment with intravitreal antivascular endothelial growth factor (VEGF). METHODS: Prospective cohort study. OCTA was performed sequentially: before (t0), 1 h (t1), 1 week (t2) and 1 month after the injection (t3), using Avan...


Variação sazonal e influência de fatores meteorológicos na incidência de descol...

Marques, JP; Rodrigues, C; Raimundo, M; Moniz, S; Trindade, F; Alfaiate, M; Figueira, J

Objetivos: Analisar a variação sazonal e a influência de fatores meteorológicos na incidência a 5 anos de descolamento regmatógeno da retina (DRR), na região centro do país e região autónoma da Madeira (RAM). Métodos: Série de casos consecutiva, retrospetiva e multicêntrica. Incluíram-se doentes submetidos a cirurgia de DRR no Centro Hospitalar e Universitário de Coimbra e Hospital Doutor Nélio Mendonça entre J...


Microincision Vitrectomy Trocars – Redefining Surgical Practices Through a New ...

Marques, JP; Azenha, C; Figueira, J

Transconjunctival microincision vitrectomy surgery (MIVS) has grown increasingly popular among vitreoretinal surgeons over the last few years. Technical advances have led to the development of cutting-edge vitrectomy systems and instruments that significantly contributed to the success of MIVS. Trocar evolution has added extra safeness and effectiveness to the technique. In the hands of an experienced surgeon, ...


Treatment of Retinal Vein Occlusion with Ranibizumab in Clinical Practice: Long...

Farinha, C; Marques, JP; Almeida, E; Baltar, A; Santos, AR; Melo, P; Costa, M; Figueira, J; Cachulo, ML; Pires, I; Silva, R

To evaluate long-term results and predictors of efficacy in patients with macular edema due to retinal vein occlusion (RVO) treated with intravitreal ranibizumab in a clinical practice setting.


A Eficácia dos Antiangiogénicos nos Olhos Vitrectomizados

Sousa, K; Costa, J; Gentil, R; Mendes, J; Freitas, R; Leite, R; Silva, R; Gomes, N; Figueira, J


Treatment of exudative age-related macular degeneration with intravitreal ranib...

Marques, I; Fonseca, P; Luz Cachulo, M; Pires, I; Figueira, J; Faria de Abreu, JR; Silva, R

PURPOSE: To evaluate the 36-month efficacy of intravitreal ranibizumab injections for choroidal neovascularization secondary to age-related macular degeneration (AMD) in real world clinical practice. METHODS: Retrospective study involving 84 eyes of 77 patients; 52 eyes completed 3 years of follow-up. Subjects were observed initially on a monthly basis and with extended follow-up intervals if signs of quiescenc...


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