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Feelings of Loneliness due to COVID‑19 Pandemic’s Home Confinement/ Quarantine ...

Pereira, Joana; Pereira, Diana; Santos, Henrique; Vieira, Ana Sofia; Marinho, Gonçalo; Figueira, Maria Luísa; Madeira, Luís

Introduction: We aimed to understand how loneliness and empathy relate to home confinement/quarantine and to explore the relation between loneliness, anxiety traits and empathy. Methods: This is an observational cross‑sectional cohort study including 364 participants. We delivered an online questionnaire composed by UCLA Loneliness scale (assessing loneliness), STAI‑Y (assessing trait anxiety), and IRI (assessi...


An Unexpected War in Ukraine: What Should we Expect? The Consequences of War am...

Di Fiorino, Mario; Marunkevych, Makym; Madeira, Luís; Figueira, Maria Luísa


Executive functions and insight in OCD : a comparative study

Manarte, Lucas; Andrade, António R.; Rosário, Linete do; Sampaio, Daniel; Figueira, Maria Luísa; Morgado, Pedro; Sahakian, Barbara J.

Background: Around 25 to 30% of patients with obsessive-compulsive disorder (OCD) do not respond to treatment. These patients have the longest duration of disease and the worst prognosis. Following years of research on this topic, insight has emerged as a potential explanation for this therapeutic resistance. Therefore, it has become important to characterize OCD patients with poor insight. Few studies have foc...


Memory awareness in patients with Major Depressive Disorder

Mendes, Tiago; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Silva, Dina; Alves, Luísa; Schmand, Ben; Simões do Couto, Frederico

Background: Subjective Memory Complaints (SMC) along with cognitive deficits are frequently observed in patients with Major Depressive Disorder (MDD). The relationship between SMC and objective memory performance in patients with MDD was evaluated, in comparison with patients with Mild Cognitive Impairment due to Alzheimer’s Disease (MCI-AD) and healthy controls (HC). Methods: Patients with MDD (n = 47), MCI-AD...


Memory awareness in patients with major depressive disorder

Mendes, Tiago; Cardoso, Sandra; Guerreiro, Manuela; Marôco, João Paulo.; Silva, Dina; Alves, Luísa; Schmand, Ben; Couto, Frederico Simões Do

Subjective Memory Complaints (SMC) along with cognitive deficits are frequently observed in patients with Major Depressive Disorder (MDD). The relationship between SMC and objective memory performance in patients with MDD was evaluated, in comparison with patients with Mild Cognitive Impairment due to Alzheimer's Disease (MCI-AD) and healthy controls (HC).


Suicidal behaviour after first-episode psychosis: results from a 1-year longitu...

Coentre, Ricardo; Fonseca, Alexandra; Mendes, Tiago; Rebelo, Ana; Fernandes, Elisabete; Levy, Pedro; Gois, Carlos; Figueira, Maria Luísa

Background: Suicide is one of the main causes of excess of premature death in psychotic patients. Published studies found that suicide risk begins in ultra-high risk of psychosis and continues in early years of the disease. Previous studies identifying predictive and risk factors associated with suicidality in first-episode psychosis (FEP) are highly inconsistent. Also, there are relatively few longitudinal stu...


Predicting epilepsy surgery outcome in adult patients: may psychiatric diagnosi...

Novais, Filipa; Pestana, Luís Câmara; Loureiro, Susana; Andrea, Mafalda; Figueira, Maria Luísa; Pimentel, José

Objective: With this study, we aimed to assess the importance of including psychiatric disorders in a comprehensive prediction model for epilepsy surgery. Methods: Ambispective observational study with a sample of adults who underwent resective surgery. Participants were evaluated, before and one year after surgery, to collect data regarding their neurological and psychiatric history. The one-year post-surgical...


Relationships between inflammatory markers and suicide risk status in major dep...

Ganança, Licínia; Galfalvy, Hanga C.; Cisneros-Trujillo, Sebastian; Basseda, Zahra; Cooper, Thomas B.; Ren, Xinguo; Figueira, Maria Luísa

Pro-inflammatory status has been implicated in depression and suicidal behaviors. Polyunsaturated fatty acids (PUFAs) and cytokines, two types of inflammatory biomarkers, have been associated with suicide, independent of depression severity. How these biomarkers relate to each other is less clear. We measured plasma phospholipid levels of arachidonic acid (AA%), docosahexaenoic acid (DHA%), and eicosapentaenoic...



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