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Recommendations for the implementation of a national lung cancer screening prog...

Fernandes, MG; Dias, M; Santos, R; Ravara, S; Fernandes, P; Firmino-Machado, J; Antunes, JP; Fernandes, O; Madureira, A; Hespanhol, V; Rodrigues, C

Lung cancer (LC) is a leading cause of cancer-related mortality worldwide. Lung Cancer Screening (LCS) programs that use low-dose computed tomography (LDCT) have been shown to reduce LC mortality by up to 25 % and are considered cost-effective. The European Health Union has encouraged its Member States to explore the feasibility of LCS implementation in their respective countries. The task force conducted a com...

Date: 2024   |   Origin: Saúde - CUF

Recommendations for the implementation of a national lung cancer screening prog...

Fernandes, MGO; Dias, M; Santos, R; Ravara, S; Fernandes, P; Firmino-Machado, J; Antunes, JP; Fernandes, O; Madureira, A; Hespanhol, V; Rodrigues, C

Lung cancer (LC) is a leading cause of cancer-related mortality worldwide. Lung Cancer Screening (LCS) programs that use low-dose computed tomography (LDCT) have been shown to reduce LC mortality by up to 25 % and are considered cost-effective. The European Health Union has encouraged its Member States to explore the feasibility of LCS implementation in their respective countries. The task force conducted a com...


Epidemiology of Psoriasis in Portugal: A Population-Based Study

Torres, T; Filipe, P; Menezes Brandão, F; Figueiredo, A; Pinto Soares, A; Sousa Basto, A; Rebelo, C; Correia, O; Ferreira, P; Brasileiro, A

Introduction: Psoriasis is a common, chronic, and inflammatory skin disorder with a high personal, social and economic burden and important implica-tions for healthcare systems. The aim of this study was to provide an epidemiological characterization of individuals with psoriasis in Portugal.Material and Methods: A large observational, cross-sectional, nationwide, population-based survey study developed by the ...

Date: 2023   |   Origin: Lusíadas Saúde

Visceral Pseudoaneurysms and the Role of Endovascular Treatment – a Case Report

Figueiredo, A; Camacho, N; Ferreira, ME

Introduction: Visceral pseudoaneurysms are pathological dilations of the visceral arteries and/or their branches. They are a rare entity but with devastating consequences given their high potential for rupture and hemorrhage. The evolution of endovascular techniques has changed the paradigm in the treatment of this entity, making it the preferred option for the elective treatment of visceral pseudoaneurysms. Cl...


Risk of Death After Paclitaxel Exposure During Femoropopliteal Artery Angioplas...

Ribeiro, T; Soares Ferreira, R; Cardoso, J; Figueiredo, A; Fidalgo, H; Bastos Gonçalves, F; Ferreira, ME

Paclitaxel molecule has been on the market since 1991 and is indicated for the treatment of multiple neoplasms. Since 2012 has been used in endovascular devices for the treatment of peripheral artery disease and have become a mainstay in the treatment of symptomatic femoro-popliteal lesions, in particular for preventing arterial restenosis. They have a proven benefit in patency and freedom-from re-intervention ...


Kinetics of radium-223 and its effects on survival, proliferation and DNA damag...

Marques, IA; Abrantes, AM; Pires, AS; Neves, AR; Caramelo, FJ; Rodrigues, T; Matafome, P; Tavares-da-Silva, E; Gonçalves, AC; Pereira, CC; Teixeira, JP

Background Metastatic castration-resistant prostate cancer (mCRPC) is associated with a very unfavorable prognosis. At this advanced stage of the disease, there are several therapeutic strategies approved in recent times, being one of them Radium-223 dichloride (Radium-223). However, its mechanisms of action and the process that conducts to cell death are not fully understood. Given this, our main goal is to ch...


Real-world data from the Portuguese Nivolumab Expanded Access Program (EAP) in ...

Figueiredo, A; Almeida, M A; Almodovar, M T; Alves, P; Araújo, A; Araújo, D; Barata, F; Barradas, L; Barroso, A; Brito, U; Camacho, E; Canário, D

OBJECTIVE: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. METHODS: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...

Date: 2020   |   Origin: Saúde - CUF

Real-world data from the Portuguese Nivolumab Expanded Access Program (EAP) in ...

Figueiredo, A; Almeida, MA; Almodovar, MT; Alves, P; Araújo, A; Araújo, D, et al.

OBJECTIVE: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. METHODS: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...


Hip Desarthrodesis - Report of Three Cases

Moura, DL; Figueiredo, A

Hip desarthrodesis, which is the conversion of an arthrodesis or of a surgical bone fusion into a hip replacement arthroplasty, is a difficult and challenging operation because of the need of a joint reconstruction in cases with bone fusion and an often long-term immobilization between the femur and the acetabulum, with important anatomic changes, retractions of adjacent soft tissues, and an associated limb sho...


Hemophagocytic lymphohistiocytosis, Leishmania and Epstein-Barr infection: an u...

Costa, F; Miranda, A; Figueiredo, A; Correia, P

Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of abnormal excessive immune activation, with signs and symptoms of excessive inflammation. Case report: 18-months-old girl admitted for persistent fever for the past two months. No other symptoms associated. History of a trip to the north of Portugal with contact with dogs. On examination: ill-appearance, pale and hepatosplenomegaly. Laborato...


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